Evidence map›Paper›PMID 21540016›Full record

ArticleSeminars in cutaneous medicine and surgery2011

New agents for prevention of ultraviolet-induced nonmelanoma skin cancer.

William L Camp, Jennifer W Turnham, Mohammad Athar, Craig A Elmets

Abstract read
In one paragraph

Article in Seminars in cutaneous medicine and surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Xeroderma Pigmentosum: General Aspects and Management.Journal of personalized medicine · 2021
    Review
  3. Prevention of Skin Carcinogenesis by the Non-β-blocking R-carvedilol Enantiomer.Cancer prevention research (Philadelphia, Pa.) · 2021
    Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

William L CampDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jennifer W Turnham
Mohammad Athar
Craig A Elmets

Funding

UAB Skin Diseases Research CenterP30AR050948 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ELMETS, CRAIG A · 2004 to 2013
$5.5M
Role of p53 and ptc tumor suppressive pathways in BCCs development and preventionR01ES015323 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ATHAR, MOHAMMAD · 2006 to 2010
$1.7M
Inhibiting Multiple Molecular Targets for Preventing Non-Melanoma Skin CancerR01CA138998 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ATHAR, MOHAMMAD · 2011 to 2015
$1.5M
Training in Investigative DermatologyT32AR053458 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ELMETS, CRAIG A · 2006 to 2010
$861k
NCI NIH HHS R01 CA138998NIAMS NIH HHS P30 AR050948NIAMS NIH HHS T32 AR053458NIEHS NIH HHS R01 ES015323
6 · The paper itself

Abstract

With the incidence of nonmelanoma skin cancer on the rise, current prevention methods, such as the use of sunscreens, have yet to prove adequate to reverse this trend. There has been considerable interest in identifying compounds that will inhibit or reverse the biochemical changes required for skin cancers to develop, either by pharmacologic intervention or by dietary manipulation. By targeting different pathways identified as important in the pathogenesis of nonmelanoma skin cancers, a combination approach with multiple agents or the addition of chemopreventative agents to topical sunscreens may offer the potential for novel and synergistic therapies in treating nonmelanoma skin cancer.

Indexed as

Diet, Fat-RestrictedPhotochemotherapyAnilidesBasal Cell CarcinomaCarcinoma, Squamous CellCarotenoidsCell Transformation, NeoplasticCyclooxygenase 2 InhibitorsDNA Repair EnzymesEflornithineFlavonoidsGenisteinHumansKeratosis, ActinicLycopenePhenolsAnilidesCarotenoidsCyclooxygenase 2 InhibitorsDNA Repair EnzymesEflornithineFlavonoidsGenisteinHhAntag691LycopenePhenolsPolyphenolsPyridinesRetinoidsSunscreening Agents

Identifiers

PMID21540016
PMCPMC3488433

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.