ArticleProceedings of the National Academy of Sciences of the United States of America1990
A pair of tandemly repeated genes code for gp24, a putative adhesion protein of Dictyostelium discoideum.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 21 citations in OpenAlex.
- Evolution of promoter sequences: elements of a canonical promoter for prespore genes of Dictyostelium.Journal of molecular evolution · 1996Article
- Article
- REMI-RFLP mapping in the Dictyostelium genome.Genetics · 1994Article
- The molecular basis for alternative splicing of the CABP1 transcripts in Dictyostelium discoideum.Nucleic acids research · 1990Article
- Nuclear pre-mRNA introns: analysis and comparison of intron sequences from Tetrahymena thermophila and other eukaryotes.Nucleic acids research · 1990Article
- New nucleotide sequence data on the EMBL File Server.Nucleic acids research · 1990Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The glycoprotein gp24 has been implicated in cell-cell adhesion of Dictyostelium discoideum. We have used a cDNA clone that codes for gp24 to screen cloned genomic fragments. Two closely linked genes (GP24A and GP24B) were recognized that generate mRNAs of about 650 base pairs after excision of a small intron and addition of poly(A). They appear to have arisen by tandem duplication of about 800 base pairs, followed by divergence. These genes are expressed within a few hours of the initiation of development; their mRNAs accumulate to a peak at 12 hr and persist until culmination. Both genes have short guanine-rich sequences (G boxes) upstream that have been shown to be involved in transcriptional regulation of other genes expressed during development of Dictyostelium. Their mRNAs code for proteins that are 85% identical. GP24A and GP24B mRNAs code for proteins with a hydrophobic domain followed by a highly charged carboxyl-terminal domain.
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Registered trials
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