ReviewBirth defects research. Part A, Clinical and molecular teratology2011
What chick and mouse models have taught us about the role of the endocardium in congenital heart disease.
Review in Birth defects research. Part A, Clinical and molecular teratology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
- Mechanisms of mitral valve development and disease.Frontiers in cardiovascular medicine · 2026Review
- Endocardial-Myocardial Interactions During Early Cardiac Differentiation and Trabeculation.Frontiers in cardiovascular medicine · 2022Review
- Mending a broken heart:Disease models & mechanisms · 2021Review
- Biallelic loss-of-function variants in PLD1 cause congenital right-sided cardiac valve defects and neonatal cardiomyopathy.The Journal of clinical investigation · 2021Article
- Loss of flow responsive Tie1 results in Impaired Aortic valve remodeling.Developmental biology · 2019Article
- Myocardial differentiation is dependent upon endocardial signaling during early cardiogenesisDevelopment (Cambridge, England) · 2019Article
- Endothelial/Epithelial Mesenchymal Transition in Ascending Aortas of Patients With Bicuspid Aortic Valve.Frontiers in cardiovascular medicine · 2019Review
- Muscleblind-like 1 is required for normal heart valve development in vivo.BMC developmental biology · 2015Article
- A detailed comparison of mouse and human cardiac development.Pediatric research · 2014Article
- Critical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.Cardiovascular research · 2014Article
- Myocardial contraction and hyaluronic acid mechanotransduction in epithelial-to-mesenchymal transformation of endocardial cells.Biomaterials · 2014Article
- The chick embryo as an expanding experimental model for cancer and cardiovascular research.Developmental dynamics : an official publication of the American Association of Anatomists · 2014Review
- tal1 Regulates the formation of intercellular junctions and the maintenance of identity in the endocardium.Developmental biology · 2013Article
- Nfatc1 directs the endocardial progenitor cells to make heart valve primordium.Trends in cardiovascular medicine · 2013Review
- RNA binding proteins in the regulation of heart development.The international journal of biochemistry & cell biology · 2013Review
- Disruption of canonical TGFβ-signaling in murine coronary progenitor cells by low level arsenic.Toxicology and applied pharmacology · 2013Article
- Spatial transcriptional profile of the chick and mouse endocardial cushions identify novel regulators of endocardial EMT in vitro.Journal of molecular and cellular cardiology · 2013Article
- Article
- Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.Development (Cambridge, England) · 2012Article
- Twist factor regulation of non-cardiomyocyte cell lineages in the developing heart.Differentiation; research in biological diversity · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Specific cell and tissue interactions drive the formation and function of the vertebrate cardiovascular system. Although much attention has been focused on the muscular components of the developing heart, the endocardium plays a key role in the formation of a functioning heart. Endocardial cells exhibit heterogeneity that allows them to participate in events such as the formation of the valves, septation of the outflow tract, and trabeculation. Here we review, the contributions of the endocardium to cardiovascular development and outline useful approaches developed in the chick and mouse that have revealed endocardial cell heterogeneity, the signaling molecules that direct endocardial cell behavior, and how these insights have contributed to our understanding of cardiovascular development and disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.