ReviewBirth defects research. Part A, Clinical and molecular teratology2011
The emerging genetic landscape underlying cardiac conduction system function.
Review in Birth defects research. Part A, Clinical and molecular teratology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- CoordinatedeLife · 2025Article
- Hippo-Yap Signaling Maintains Sinoatrial Node Homeostasis.Circulation · 2022Article
- Familial risk of atrioventricular block in first-degree relatives.Heart (British Cardiac Society) · 2022Article
- A Novel Missense Mutation inGenes · 2021Article
- Transcriptional Patterning of the Ventricular Cardiac Conduction System.Circulation research · 2020Article
- ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.Circulation research · 2020Article
- Using Gjd3-CreEGFP mice to examine atrioventricular node morphology and composition.Scientific reports · 2019Article
- Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles.Journal of molecular and cellular cardiology · 2018Article
- Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology.Circulation. Genomic and precision medicine · 2018Article
- Phenotypically silent Cre recombination within the postnatal ventricular conduction system.PloS one · 2017Article
- MyoR modulates cardiac conduction by repressing Gata4.Molecular and cellular biology · 2015Article
- Cardiac-specific inducible and conditional gene targeting in mice.Circulation research · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Proper function of an organized Cardiac Conduction System (CCS) is vital to the survival of metazoans ranging from fly to man. The routine use of non-invasive electrocardiogram measures in the diagnosis and monitoring of cardiovascular health has established a trove of reliable CCS functional data in both normal and diseased cardiac states. Recent combination of echocardiogram (ECG) data with genome-wide association studies has identified genomic regions implicated in ECG variability which impact CCS function. In this study, we review the substantial recent progress in this area, highlighting the identification of novel loci, confirming the importance of previously implicated loci in CCS function, and exploring potential links between genes with important roles in developmental processes and variation in function of the CCS.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.