Evidence map›Paper›PMID 21538235›Full record

ReviewJournal of microbiology (Seoul, Korea)2011

Candida albicans, a major human fungal pathogen.

Joon Kim, Peter Sudbery

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of microbiology (Seoul, Korea), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 209 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
209citing papers in PubMed, 1 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

209 citing papers in PubMed, 1 synthesis or guideline pooled it, 478 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Evaluation of the antifungal potential of N, N chelating iridium(III) complexes.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
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  4. Review
  5. Article
  6. Article
  7. Mating type and genotyping ofIranian journal of microbiology · 2026
    Article
  8. Article
  9. Response ofmSphere · 2026
    Article
  10. Review
  11. Transboundary and emerging diseases · 2026
    Article
  12. Article
  13. Bioactive Constituents ofDrug design, development and therapy · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Acridine Derivatives as Antifungal and Antivirulence Agents AgainstInternational journal of molecular sciences · 2025
    Article
  19. Article
  20. Anti-candida activity ofIranian journal of microbiology · 2025
    Article

149 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Joon KimLaboratory of Biochemistry, School of Life Sciences and Biotechnology, Korea University, Seoul 136-701, Republic of Korea.
Peter Sudbery
Korea University · KRUniversity of Sheffield · GB

Funding

Biotechnology and Biological Sciences Research Council BB/E003273/1
6 · The paper itself

Abstract

Candida albicans is the most common human fungal pathogen (Beck-Sague and Jarvis, 1993). It is normally a harmless commensal organism. However, it is a opportunistic pathogen for some immunologically weak and immunocompromised people. It is responsible for painful mucosal infections such as the vaginitis in women and oral-pharangeal thrush in AIDS patients. In certain groups of vulnerable patients it causes severe, life-threatening bloodstream infections and it causes severe, life-threatening bloodstream infections and subsequent infections in the internal organs. There are various fascinating features of the C. albicans life cycle and biology that have made the pathogen the subject of extensive research, including its ability to grow in unicellular yeast, pseudohyphal, and hyphal forms (Fig. 1A); its ability to switch between different but stable phenotypic states, and the way that it retains the ability to mate but apparently loses the ability to go through meiosis to complete the sexual cycle. This research has been greatly facilitated by the derivation of the complete C. albicans genome sequence (Braun et al., 2005), the development of a variety of molecular tools for gene manipulation, and a store of underpinning knowledge of cell biology borrowed from the distantly related model yeast Saccharomyces cerevisiae (Berman and Sudbery, 2002; Noble and Johnson, 2007). This review will provide a brief overview of the importance of C. albicans as a public health issue, the experimental tools developed to study its fascinating biology, and some examples of how these have been applied.

Indexed as

Candida albicansCandidiasisFungal ProteinsGenetics, MicrobialGenome, FungalHumansImmunocompromised HostVirulenceVirulence FactorsFungal ProteinsVirulence Factors

Identifiers

PMID21538235
OpenAlexW2069635419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.