ArticleClinical research in cardiology : official journal of the German Cardiac Society2011
Diagnostic accuracy of NT-proBNP ratio (BNP-R) for early diagnosis of tachycardia-mediated cardiomyopathy: a pilot study.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Heart failure and atrial flutter: a systematic review of current knowledge and practices.ESC heart failure · 2021Pooled it
- Arrhythmia-induced cardiomyopathy: focus on atrial fibrillation.Nature reviews. Cardiology · 2026Review
- Arrhythmia-Induced Cardiomyopathy in Atrial Fibrillation: Pathogenesis, Diagnosis, and Treatment.Life (Basel, Switzerland) · 2025Review
- Characterization of arrhythmia-induced cardiomyopathy using magnetic resonance imaging in patients with persistent atrial fibrillation and left ventricular systolic dysfunction - insights from DECAAF II.European journal of heart failure · 2025Article
- Definition and management of arrhythmia-induced cardiomyopathy: findings from the European Heart Rhythm Association survey.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Article
- Time to Recovery from Systolic Dysfunction Correlates with Left Ventricular Fibrosis in Arrhythmia-Induced Cardiomyopathy.Life (Basel, Switzerland) · 2024Article
- Catheter Ablation for the Management of Atrial Fibrillation: An Update of the Literature.Life (Basel, Switzerland) · 2023Review
- Review
- Emerging concepts in heart failure management and treatment: focus on tachycardia-induced cardiomyopathy.Drugs in context · 2023Review
- Rate of atrial fibrillation and flutter induced tachycardiomyopathy in a cohort of hospitalized patients with heart failure and detection of indicators for improved diagnosis.Frontiers in cardiovascular medicine · 2022Article
- Tachycardiomyopathy in Patients without Underlying Structural Heart Disease.Journal of clinical medicine · 2019Article
- Tachycardia induced Cardiomyopathy.Korean circulation journal · 2019Review
- Turkish Society of Cardiology consensus paper on management of arrhythmia-induced cardiomyopathy.Anatolian journal of cardiology · 2019Article
- Pathophysiology, diagnosis and treatment of tachycardiomyopathy.Heart (British Cardiac Society) · 2017Review
- Arrhythmia-Induced Cardiomyopathies: Mechanisms, Recognition, and Management.Journal of the American College of Cardiology · 2015Review
- Non-reentrant atrioventricular nodal tachycardia.Clinical research in cardiology : official journal of the German Cardiac Society · 2013Article
- Prognostic value of B-type natriuretic peptide (BNP) and its potential role in guiding fluid therapy in critically ill septic patients.Scandinavian journal of trauma, resuscitation and emergency medicine · 2012Article
- Arrhythmia-Induced Cardiomyopathy: Prevalent, Under-recognized, Reversible.Journal of atrial fibrillationArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhen heart failure and tachycardia occur simultaneously, a useful diagnostic tool for early discrimination of patients with benign tachycardia-mediated cardiomyopathy (TMC) versus major structural heart disease (MSHD) is not available. Such a tool is required to prevent unnecessary and wearing diagnostics in patients with reversible TMC. Moreover, it could lead to early additional diagnostics and therapeutic approaches in patients with MSHD.
methodsA total of 387 consecutive patients with supraventricular arrhythmia underwent assessment at a single center. Of these patients, 40 fulfilled the inclusion criteria with a resting heart rate ≥100 bpm and an impaired left ventricular ejection fraction <40%. In all patients, successful electrical cardioversion was performed. At baseline, day 1 and weekly for 4 weeks, levels of NT-proBNP and echocardiographic parameters were evaluated. An NT-proBNP ratio (BNP-R) was calculated as a quotient of baseline NT-proBNP/follow-up NT-proBNP. After 4 weeks, cardiac catheterization was performed to identify patients with a final diagnosis of TMC versus MSHD.
resultsInitial NT-proBNP concentrations were elevated and consecutively decreased after cardioversion in all patients. Multivariate regression and ROC analysis revealed that BNP-R discriminated between patients with TMC versus MSHD independent and superior to all other variables. The area under the ROC curve for BNP-R to detect TMC was 0.90 (95% CI 0.79-1.00; p < 0.001) after 1 week and 0.995 (95% CI 0.99-1.00; p < 0.0001) after 4 weeks. One week after cardioversion already, a BNP-R cutoff ≥2.3 was useful for TMC diagnosis indicated by an accuracy of 90%, sensitivity of 84% and specificity of 95%.
conclusionBNP-R was found to be highly accurate for the early diagnosis of TMC.
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