ReviewCellular and molecular life sciences : CMLS2011
Axonal commissures in the central nervous system: how to cross the midline?
Review in Cellular and molecular life sciences : CMLS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Bi-allelic variants in FSD1L cause a neurodevelopmental disorder overlapping with L1 syndrome.American journal of human genetics · 2026Article
- Article
- A cell-autonomous role for primary cilium-mediated signaling in long-range commissural axon guidance.Development (Cambridge, England) · 2024Article
- Ventricular Netrin-1 deficiency leads to defective pyramidal decussation and mirror movement in mice.Cell death & disease · 2024Article
- Intracellular Trafficking Mechanisms that Regulate Repulsive Axon Guidance.Neuroscience · 2023Review
- Article
- The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression.Nucleic acids research · 2019Article
- Development of piriform cortex interhemispheric connections via the anterior commissure: progressive and regressive strategies.Brain structure & function · 2018Article
- Contactin-2/TAG-1, active on the front line for three decades.Cell adhesion & migration · 2017Article
- Behavioral Consequences of a Bifacial Map in the Mouse Somatosensory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Non cell-autonomous role of DCC in the guidance of the corticospinal tract at the midline.Scientific reports · 2017Article
- Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance.BMC neuroscience · 2016Article
- Commissural axon navigation: Control of midline crossing in the vertebrate spinal cord by the semaphorin 3B signaling.Cell adhesion & migration · 2016Review
- IMP2 axonal localization, RNA interactome, and function in the development of axon trajectories.Development (Cambridge, England) · 2016Article
- Canonical wnt signaling is required for commissural axon guidance.Developmental neurobiology · 2016Article
- Expression Patterns of Extracellular Matrix Proteins during Posterior Commissure Development.Frontiers in neuroanatomy · 2016Article
- Old friends, new story: The role of Slit2C signaling through PlexinA1.Cell adhesion & migration · 2015Article
- One hand clapping: lateralization of motor control.Frontiers in neuroanatomy · 2015Review
- PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments.Nature neuroscience · 2015Article
- Semaphorin 6B acts as a receptor in post-crossing commissural axon guidance.Development (Cambridge, England) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organisms with bilateral symmetry elaborate patterns of neuronal projections connecting both sides of the central nervous system at all levels of the neuraxis. During development, these so-called commissural projections navigate across the midline to innervate their contralateral targets. Commissural axon pathfinding has been extensively studied over the past years and turns out to be a highly complex process, implicating modulation of axon responsiveness to the various guidance cues that instruct axon trajectories towards, within and away from the midline. Understanding the molecular mechanisms allowing these switches of response to take place at the appropriate time and place is a major challenge for current research. Recent work characterized several instructive processes controlling the spatial and temporal fine-tuning of the guidance molecular machinery. These findings illustrate the molecular strategies by which commissural axons modulate their sensitivity to guidance cues during midline crossing and show that regulation at both transcriptional and post-transcriptional levels are crucial for commissural axon guidance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.