Evidence map›Paper›PMID 21538038›Full record

ArticleInfection2011

Seronegative visceral leishmaniasis with relapsing and fatal course following rituximab treatment.

A Casabianca, M Marchetti, F Zallio, E Feyles, E Concialdi, E Ferroglio, A Biglino

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Infection, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

A CasabiancaInfectious and Tropical Diseases Unit, Cardinal Massaja Hospital, Corso Dante 202, 14100 Asti, Italy. casabianca@asl.at.it
M Marchetti
F Zallio
E Feyles
E Concialdi
E Ferroglio
A Biglino
Azienda Sanitaria Locale di Asti · ITHospital for Tropical Diseases · VNUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both the presentation and clinical course of visceral leishmaniasis (VL) may be atypical in immunosuppressed subjects, often resulting in delayed diagnosis and treatment. We describe a case of VL characterized by negative serologic testing, a relapsing course, and a fatal outcome 2 years after the patient had been successfully treated for non-Hodgkin's lymphoma with rituximab. Diagnosis of VL may be further delayed or even missed in patients treated with drugs that interfere with specific antibody production unless specific diagnostic methods, such as bone marrow examination and parasite DNA amplification/detection, are routinely employed.

Indexed as

AgedAmphotericin BAntibodies, Monoclonal, Murine-DerivedAntineoplastic AgentsAntiprotozoal AgentsBone MarrowFatal OutcomeFemaleHumansImmunocompromised HostItalyLeishmania infantumLeishmaniasis, VisceralLeukocytes, MononuclearLymphoma, Non-HodgkinPolymerase Chain ReactionAmphotericin BAntibodies, Monoclonal, Murine-DerivedAntineoplastic AgentsAntiprotozoal Agentsliposomal amphotericin BRituximab

Identifiers

PMID21538038
OpenAlexW1981470754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.