Trial reportAnnals of surgical oncology2011
Therapeutic surgical management of palpable melanoma groin metastases: superficial or combined superficial and deep groin lymph node dissection.
Trial report in Annals of surgical oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Ultrasound, CT, MRI, or PET-CT for staging and re-staging of adults with cutaneous melanoma.The Cochrane database of systematic reviews · 2019Pooled it
- Conservative lymph node surgery for patients with stage III melanoma: a prospective longitudinal cohort.The oncologist · 2025Article
- Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).Annals of surgical oncology · 2022Article
- Neoadjuvant Immune Checkpoint Inhibitor Therapy in Melanoma: Efficacy, Safety and Timing.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2022Review
- Malignant melanoma: evolving practice management in an era of increasingly effective systemic therapies.Current problems in surgery · 2022Review
- Extent of Groin Dissection in Melanoma: A Mixed-Methods, Population-Based Study of Practice Patterns and Outcomes.Current oncology (Toronto, Ont.) · 2021Article
- Review
- Non-surgical management of primary invasive melanoma.The Journal of dermatological treatment · 2021Article
- Survival of sentinel node biopsy versus observation in intermediate-thickness melanoma: A Dutch population-based study.PloS one · 2021Article
- Laparoscopically assisted ilio-inguinal lymph node dissection versus inguinal lymph node dissection in melanoma.Melanoma management · 2020Article
- Surgical Considerations and Systemic Therapy of Melanoma.The Surgical clinics of North America · 2020Review
- Surgery for Metastatic Melanoma: an Evolving Concept.Current oncology reports · 2019Review
- Optimal extent of completion lymphadenectomy for patients with melanoma and a positive sentinel node in the groin.The British journal of surgery · 2018Article
- Robotic-Assisted Transperitoneal Pelvic Lymphadenectomy for Metastatic Melanoma: Early Outcomes Compared with Open Pelvic Lymphadenectomy.Journal of the American College of Surgeons · 2016Article
- Risk Factors for Positive Deep Pelvic Nodal Involvement in Patients with Palpable Groin Melanoma Metastases: Can the Extent of Surgery be Safely Minimized? : A Retrospective, Multicenter Cohort Study.Annals of surgical oncology · 2015Article
- Superficial and deep lymph node dissection for stage III cutaneous melanoma: clinical outcome and prognostic factors.World journal of surgical oncology · 2013Article
- Preoperative ultrasound is not useful for identifying nodal metastasis in melanoma patients undergoing sentinel node biopsy: preoperative ultrasound in clinically node-negative melanoma.Annals of surgical oncology · 2012Article
- Role of a skin bridge incision and prophylactic incisional negative-pressure wound therapy in the prevention of surgical site infection after inguinal lymph node dissection.Canadian journal of surgery. Journal canadien de chirurgieArticle
- Predictors of complication after groin dissection: a single-centre experience.Canadian journal of surgery. Journal canadien de chirurgieArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundManagement of patients with clinically detectable lymph node metastasis to the groin is by ilioinguinal or combined superficial and deep groin dissection (CGD) according to most literature, but in practice superficial groin dissection (SGD) only is still performed in some centers. The aim of this study is to evaluate the experience in CGD versus SGD patients in our center.
methodsBetween 1991 and 2009, 121 therapeutic CGD and 48 SGD were performed in 169 melanoma patients with palpable groin metastases at our institute. Median follow-up was 20 and, for survivors, 45 months.
resultsIn this heterogeneous group of patients, overall (OS) and disease-free survival, local control rates, and morbidity rates were not significantly different between CGD and SGD patients. However, CGD patients had a trend towards more chronic lymphedema. Superficial lymph node ratio, the number of positive superficial lymph nodes, and the presence of deep nodes were prognostic factors for survival. CGD patients with involved deep lymph nodes (24.8%) had estimated 5-year OS of 12% compared with 40% with no involved deep lymph nodes (p=0.001). Preoperative computed tomography (CT) scan had high negative predictive value of 91% for detection of pelvic nodal involvement.
conclusionsThis study demonstrated that survival and local control do not differ for patients with palpable groin metastases treated by CGD or SGD. Patients without pathological iliac nodes on CT might safely undergo SGD, while CGD might be reserved for patients with multiple positive nodes on SGD and/or positive deep nodes on CT scan.
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