ArticleWorld journal of diabetes2010
Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation.
Article in World journal of diabetes, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Effect of vitamin D on oxidative stress and serum inflammatory factors in the patients with type 2 diabetes.Journal of clinical laboratory analysis · 2022Trial
- Anti-inflammatory effects of cannabidiol in the treatment of type 1 diabetes: A mini review.World journal of diabetes · 2025Review
- Diabetic retinopathy and Alzheimer's disease: Convergence of the unfolded protein response in neurodegeneration.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Review
- Role of Lnc-RNAs in the Pathogenesis and Development of Diabetic Retinopathy.International journal of molecular sciences · 2023Review
- Inhibition of Galectins and the P2X7 Purinergic Receptor as a Therapeutic Approach in the Neurovascular Inflammation of Diabetic Retinopathy.International journal of molecular sciences · 2023Review
- Elevated number and density of macrophage-like cell as a novel inflammation biomarker in diabetic macular edema.Scientific reports · 2023Article
- Biochemical Functions and Clinical Characterizations of the Sirtuins in Diabetes-Induced Retinal Pathologies.International journal of molecular sciences · 2022Review
- Cannabidiol (CBD) Use in Type 2 Diabetes: A Case Report.Diabetes spectrum : a publication of the American Diabetes Association · 2021Article
- Chinese Medicines in Diabetic Retinopathy Therapies.Chinese journal of integrative medicine · 2019Review
- Cell-cell communication in diabetic retinopathy.Vision research · 2017Review
- Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Müller Cells of Diabetic Human and Rodent Retina.Investigative ophthalmology & visual science · 2017Article
- Adenosine Deaminase-2-Induced Hyperpermeability in Human Retinal Vascular Endothelial Cells Is Suppressed by MicroRNA-146b-3p.Investigative ophthalmology & visual science · 2017Article
- Age and diabetes related changes of the retinal capillaries: An ultrastructural and immunohistochemical study.International journal of immunopathology and pharmacology · 2016Article
- Neuroinflammatory responses in diabetic retinopathy.Journal of neuroinflammation · 2015Review
- Sigma receptor ligand, (+)-pentazocine, suppresses inflammatory responses of retinal microglia.Investigative ophthalmology & visual science · 2014Article
- Role of P2X7 receptors in the development of diabetic retinopathy.World journal of diabetes · 2014Review
- The role of microglia in diabetic retinopathy.Journal of ophthalmology · 2014Review
- Matrix metalloproteinase-10 plays an active role in microvascular complications in type 1 diabetic patients.Diabetologia · 2013Article
- An Aqueous Extract of Radix Astragali, Angelica sinensis, and Panax notoginseng Is Effective in Preventing Diabetic Retinopathy.Evidence-based complementary and alternative medicine : eCAM · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetic retinopathy is a leading cause of blindness among working-age adults. Despite many years of research, treatment options for diabetic retinopathy remain limited and with adverse effects. Discovery of new molecular entities with adequate clinical activity for diabetic retinopathy remains one of the key research priorities in ophthalmology. This review is focused on the therapeutic effects of cannabidiol (CBD), a non-psychoactive native cannabinoid, as an emerging and novel therapeutic modality in ophthalmology based on systematic studies in animal models of inflammatory retinal diseases including diabetic retinopathy - a retinal disease associated with vascular-neuroinflammation. Special emphasis is placed on novel mechanisms which may shed light on the pharmacological activity associated with CBD preclinically. These include a self-defence system against inflammation and neurodegeneration mediated by inhibition of equilibrative nucleoside transporter and activation of adenosine receptor by treatment with CBD.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.