Evidence map›Paper›PMID 21537371›Full record

ArticleCase reports in dermatology2010

Sequential acral lentiginous melanomas of the foot.

Jiro Uehara, Yasuhiro Ito, Ichiro Takahashi, Masaru Honma, Akemi Ishida-Yamamoto, Shinobu Matsuo, Hajime Iizuka

Abstract readCase Reports
In one paragraph

Article in Case reports in dermatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiro UeharaDepartment of Dermatology, Asahikawa Medical College, Asahikawa, Japan.
Yasuhiro Ito
Ichiro Takahashi
Masaru Honma
Akemi Ishida-Yamamoto
Shinobu Matsuo
Hajime Iizuka

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 64-year-old Japanese woman had a lightly brown-blackish pigmented macule (1.2 cm in diameter) on the left sole of her foot. She received surgical excision following a diagnosis of acral lentiginous melanoma (ALM), which was confirmed histopathologically. One month after the operation, a second melanoma lesion was noticed adjacent to the grafted site. Histopathologically, the two lesions had no continuity, but HMB-45 and cyclin D(1) double-positive cells were detected not only on aggregates of atypical melanocytes but also on single cells near the cutting edge of the first lesion. The unique occurrence of a sequential lesion of a primary melanoma might be caused by stimulated subclinical field cells during the wound healing process following the initial operation. This case warrants further investigation to establish the appropriate surgical margin of ALM lesions.

Indexed as

Acral lentiginous melanomaCyclin D1Field cell modelMelanoma spreadPrimary melanomaSurgical margins

Identifiers

PMID21537371
PMCPMC3085035

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.