ArticleAntimicrobial agents and chemotherapy2011
In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics.
Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 54 citations in OpenAlex.
- Worldwide distribution of human pythosis and biological characteristics of aFrontiers in medicine · 2025Article
- Cutaneous Lagenidium deciduum infection in a patient with relapsed acute myeloid leukemia.BMC infectious diseases · 2024Article
- Treating Pythiosis with Antibacterial Drugs Targeting Protein Synthesis: An Overview.Journal of fungi (Basel, Switzerland) · 2024Review
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- Selection of an Appropriate In Vitro Susceptibility Test for Assessing Anti-Journal of fungi (Basel, Switzerland) · 2022Article
- Pythium insidiosum keratitis reported in China, raising the alertness to this fungus-like infection: a case series.Journal of medical case reports · 2021Article
- Clinical Outcomes of Radical Surgery and Antimicrobial Agents in Vascular Pythiosis: A Multicenter Prospective Study.Journal of fungi (Basel, Switzerland) · 2021Article
- Human Pythiosis: Emergence of Fungal-Like Organism.Mycopathologia · 2020Review
- Successful management of cutaneous paralagenidiosis in a dog treated with mefenoxam, minocycline, prednisone, and hyperbaric oxygen therapy.Medical mycology case reports · 2020Article
- Review
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- Successful medical management ofAmerican journal of ophthalmology case reports · 2019Article
- Analysis of xanthyletin and secondary metabolites from Pseudomonas stutzeri ST1302 and Klebsiella pneumoniae ST2501 against Pythium insidiosum.BMC microbiology · 2019Article
- Efficacy of Azithromycin and Miltefosine in Experimental Systemic Pythiosis in Immunosuppressed Mice.Antimicrobial agents and chemotherapy · 2019Article
- Article
- In Vitro Synergism between Azithromycin or Terbinafine and Topical Antimicrobial Agents against Pythium insidiosum.Antimicrobial agents and chemotherapy · 2016Article
- The Disulfide Bond of the Peptide Thanatin Is Dispensible for Its Antimicrobial Activity In Vivo and In Vitro.Antimicrobial agents and chemotherapy · 2016Article
- In Vitro and In Vivo Antimicrobial Activities of Minocycline in Combination with Azithromycin, Clarithromycin, or Tigecycline against Pythium insidiosum.Antimicrobial agents and chemotherapy · 2016Article
- Combat-Related Pythium aphanidermatum Invasive Wound Infection: Case Report and Discussion of Utility of Molecular Diagnostics.Journal of clinical microbiology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe the in vitro activity of macrolides and tetracycline antibiotics against Pythium insidiosum. The MICs were determined according to CLSI procedures (visual MIC) and by a colorimetric method [3-(4,5-dimethyl-2-thiazyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT)]. The lowest geometric mean (GM) MIC (MICs in μg/ml) (0.39 and 0.7 by visual reading and colorimetric method, respectively) and MIC ranges (0.125 to 2.0) were obtained for minocycline, while the highest MICs were shown for erythromycin (GM of 7.58 and 12.25 by visual reading and colorimetric method, respectively, and MIC ranged from 2 to 32). This significant in vitro activity makes these classes of antibiotics good candidates for experimental treatment of pythiosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.