Evidence map›Paper›PMID 21536990›Full record

ReviewHypertension (Dallas, Tex. : 1979)2011

Autonomic-immune-vascular interaction: an emerging concept for neurogenic hypertension.

Jasenka Zubcevic, Hidefumi Waki, Mohan K Raizada, Julian F R Paton

Registry-linked trialAbstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06282965 (A Randomized, Double-blind, Placebo Controlled Study of the Safety and Efficacy of Angiotensin), which is not on this map. Cited by 96 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06282965 phase1 / phase2recruitingnot on this mapstarted 2024, after this paper: background citation

A Randomized, Double-blind, Placebo Controlled Study of the Safety and Efficacy of Angiotensin (1-7) in Persons With Moderate to Severe Traumatic Brain Injury (TBI)

TypeinterventionalSponsorUniversity of ArizonaRan2024 to 2027Enrolled90ConditionsTraumatic Brain InjuryArmsAngiotensin (1-7), Sterile saline
3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Association of alpha-ADD1 Gene and Hypertension Risk: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Efficacy of Orexin Receptor Antagonist for Postoperative Atrial Fibrillation in Patients Who Underwent Off-Pump Coronary Artery Bypass Grafting.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Gut-brain-bone marrow axis in hypertension.Current opinion in nephrology and hypertension · 2021
    Review
  16. Article
  17. Article
  18. Immunity and Hypertension.Acta physiologica (Oxford, England) · 2021
    Review
  19. Article
  20. Review

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jasenka ZubcevicDepartment of Physiology and Functional Genomics, McKnight Brain Institute, 1600 SW Archer Rd, Gainesville, FL 32610, USA.
Hidefumi Waki
Mohan K Raizada
Julian F R Paton

Funding

Brain Angiotensin In Hypertensive Neurons in CultureR37HL033610 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 2003 to 2012
$5.8M
Angiotensin-Converting Enzyme2 in Vascular Endothelial FunctionR01HL102033 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 2010 to 2019
$4.3M
British Heart Foundation RG/07/006/23634NHLBI NIH HHS R01 HL102033NHLBI NIH HHS R37 HL033610NHLBI NIH HHS R37 HL33610
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAutonomic Nervous SystemBlood-Brain BarrierBlood VesselsHumansHypertensionImmune SystemInflammationModels, Biological

Identifiers

PMID21536990
PMCPMC3105900

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.