Genetic indeterminism, the 5-HTTLPR, and the paths forward in neuropsychiatric genetics.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. 5-HTTLPR polymorphism is linked to neural mechanisms of selective attention in preschoolers from lower socioeconomic status backgrounds.Developmental cognitive neuroscience · 2016
   Article
2. Gene-environment interaction in major depression: focus on experience-dependent biological systems.Frontiers in psychiatry · 2015
   Review
3. Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome.Molecular autism · 2013
   Article
4. The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: associations with cognitive vulnerability to depression in childhood.Development and psychopathology · 2013
   Article
5. No interaction between serotonin transporter gene (5-HTTLPR) polymorphism and adversity on depression among Japanese children and adolescents.BMC psychiatry · 2013
   Article
6. The serotonin transporter gene polymorphism (5HTTLPR) moderates the effect of adolescent environmental conditions on self-esteem in young adulthood: a structural equation modeling approach.Biological psychology · 2012
   Article
7. Natural and engineered coding variation in antidepressant-sensitive serotonin transporters.Neuroscience · 2011
   Article
8. Understanding risk for psychopathology through imaging gene-environment interactions.Trends in cognitive sciences · 2011
   Review

Corrections and comments

• Comment on
  The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation.2011

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as