Evidence map›Paper›PMID 21536838›Full record

ReviewThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2012

Dopaminergic neurotransmission in the human brain: new lessons from perturbation and imaging.

Ji Hyun Ko, Antonio P Strafella

Abstract readReview
In one paragraph

Review in The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 67 citations in OpenAlex.

  1. Trial
  2. Investing in the future: stimulation of the medial prefrontal cortex reduces discounting of delayed rewards.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015
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  15. Experimental evaluation of absolute quantification inJournal of applied clinical medical physics · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ji Hyun KoPET Imaging Centre, Centre for Addiction and Mental Health, University of Toronto, Ontario, Canada.
Antonio P Strafella
Centre for Addiction and Mental Health · CA

Funding

CIHR 64423
6 · The paper itself

Abstract

Dopamine plays an important role in several brain functions and is involved in the pathogenesis of several psychiatric and neurological disorders. Neuroimaging techniques such as positron emission tomography allow us to quantify dopaminergic activity in the living human brain. Combining these with brain stimulation techniques offers us the unique opportunity to tackle questions regarding region-specific neurochemical activity. Such studies may aid clinicians and scientists to disentangle neural circuitries within the human brain and thereby help them to understand the underlying mechanisms of a given function in relation to brain diseases. Furthermore, it may also aid the development of alternative treatment approaches for various neurological and psychiatric conditions.

Indexed as

NeuroimagingAnimalsBrainBrain DiseasesCognitionCorpus StriatumDopamineHumansMental DisordersNervous System DiseasesPositron-Emission TomographySynaptic TransmissionTranscranial Magnetic StimulationDopamine

Identifiers

PMID21536838
PMCPMC3479149
OpenAlexW2102170671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.