Evidence map›Paper›PMID 21536729›Full record

ArticleGenes & development2011

Sweet DREAMs for Hippo.

Frederick A Dick, Joe S Mymryk

Open access · diamondAbstract readComment
In one paragraph

Article in Genes & development, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Repressive histone methylation regulates cardiac myocyte cell cycle exit.Journal of molecular and cellular cardiology · 2018
    Article
  2. Article
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  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Frederick A DickLondon Regional Cancer Program, London, Ontario N6A 4L6, Canada. fdick@uwo.ca
Joe S Mymryk
Cancer Care Ontario · CAWestern University · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

The Hippo pathway coordinates organ size and cell proliferation. The retinoblastoma family of proteins regulates progression through the G0/G1 phase of the cell cycle. Disruption of either pathway contributes to cancer formation. Three recent studies in Genes & Development reveal how cellular proliferation is coordinated between these pathways. Here we discuss the implications of these studies and the new questions that they raise.

Indexed as

AnimalsCell CycleCellular SenescenceDyrk KinasesEmbryonic DevelopmentGene Expression RegulationHumansKv Channel-Interacting ProteinsNeoplasmsOrgan SizeProtein Serine-Threonine KinasesProtein-Tyrosine KinasesRetinoblastoma-Like Protein p130Retinoblastoma ProteinSignal TransductionDyrk KinasesKv Channel-Interacting ProteinsProtein Serine-Threonine KinasesProtein-Tyrosine KinasesRetinoblastoma-Like Protein p130Retinoblastoma Protein

Identifiers

PMID21536729
PMCPMC3084021
OpenAlexW2121858612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.