Evidence map›Paper›PMID 21536427›Full record

ReviewCurrent opinion in genetics & development2011

mRNA localization: assembly of transport complexes and their incorporation into particles.

Paul M Macdonald

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Taking a cellular road-trip: mRNA transport and anchoring.Current opinion in cell biology · 2013
    Review
  6. Article
  7. Article
  8. New insights into the regulation of RNP granule assembly in oocytes.International review of cell and molecular biology · 2012
    Review
  9. RNA transport during TMV cell-to-cell movement.Frontiers in plant science · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Paul M MacdonaldSection of Molecular Cell and Developmental Biology, Institute for Cellular and Molecular Biology, The University of Texas at Austin, 1 University Station A4800, Austin, TX 78712, USA. pmacdonald@mail.utexas.edu
The University of Texas at Austin · US

Funding

REGULATED MRNA TRANSLATION IN DROSOPHILA BODY PATTERNINGR01GM054409 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI MACDONALD, PAUL M. · 1995 to 2010
$2.1M
NIGMS NIH HHS GM54409NIGMS NIH HHS R01 GM054409
6 · The paper itself

Abstract

Localization of mRNAs to subcellular domains can enrich proteins at sites where they function. Coordination with translational control can ensure that the encoded proteins will not appear elsewhere, an important property for factors that control cell fate or body patterning. Here I focus on two aspects of mRNA localization. One is the question of how mRNAs that undergo directed transport by a shared mechanism are bound to the transport machinery, and why localization signals from these mRNAs have very diverse sequences. The second topic concerns the role of particles, in which localized mRNAs often appear. Recent evidence highlights the importance of such assemblies, and the possibility that close association of mRNAs confers community effects and a novel form of regulation.

Indexed as

RNA TransportAnimalsCell NucleusCytoplasmRNA-Binding ProteinsRNA, MessengerSignal TransductionRNA-Binding ProteinsRNA, Messenger

Identifiers

PMID21536427
PMCPMC4301680
OpenAlexW1986692329

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.