SynthesisThe Psychiatric clinics of North America2011
Psychosocial interventions for late-life major depression: evidence-based treatments, predictors of treatment outcomes, and moderators of treatment effects.
Synthesis in The Psychiatric clinics of North America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A systematic review of predictors and moderators of treatment response in psychological interventions for persisting forms of depression.The British journal of clinical psychology · 2025Pooled it
- Repetitive transcranial magnetic stimulation for late-life depression: A systematic review and meta-analysis of randomized controlled trials.The Journal of international medical research · 2025Pooled it
- Cognitive-behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis.Health technology assessment (Winchester, England) · 2021Pooled it
- Perceived Physical Health and Cognitive Behavioral Therapy vs Supportive Psychotherapy Outcomes in Adults With Late-Life Depression: A Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2024Trial
- Comparing the streamlined psychotherapy "Engage" with problem-solving therapy in late-life major depression. A randomized clinical trial.Molecular psychiatry · 2021Trial
- Therapeutic relationship in the treatment of geriatric depression with executive dysfunction.Journal of affective disorders · 2017Trial
- Clinical predictors of depression treatment outcomes in patients with coronary heart disease.Journal of psychosomatic research · 2016Trial
- Problem adaptation therapy for older adults with major depression and cognitive impairment: a randomized clinical trial.JAMA psychiatry · 2015Trial
- Neuroplasticity-based computerized cognitive remediation for treatment-resistant geriatric depression.Nature communications · 2014Trial
- Passive coping response to depressive symptoms among low-income homebound older adults: does it affect depression severity and treatment outcome?Behaviour research and therapy · 2012Trial
- Art therapy as an adjuvant treatment for depression in elderly women: a randomized controlled trial.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Trial
- Biological factors influencing depression in later life: role of aging processes and treatment implications.Translational psychiatry · 2023Review
- Effectiveness of multimodal intervention for depression, self-esteem, and quality of life among elderly people residing at selected old age homes in Jalandhar, Punjab.Journal of education and health promotion · 2023Article
- Article
- Late-life depression and the family physician.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022Article
- Depressive symptom profiles predict dementia onset and brain pathology in older persons. The AGES-Reykjavik study.Neurobiology of aging · 2022Article
- Message-based psychotherapy for older adults: A cohort comparison study.Frontiers in psychiatry · 2022Article
- Impact of the COVID-19 pandemic on working students: Results from the Labour Force Survey and the student lifestyle survey.Journal of occupational health · 2021Article
- Guided Self-Help Behavioral Activation Intervention for Geriatric Depression: Protocol for Pilot Randomized Controlled Trial.JMIR research protocols · 2020Article
- The symptom network structure of depressive symptoms in late-life: Results from a European population study.Molecular psychiatry · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
This systematic review evaluates the efficacy of psychosocial interventions for the acute treatment of late-life depression and identifies predictors of treatment outcomes and moderators of treatment effects. Problem-solving therapy, cognitive behavioral therapy, and treatment initiation and participation program have supportive evidence of efficacy, pending replication. Although the data on predictors of treatment outcomes and moderators of treatment effects are preliminary, it appears that baseline anxiety and stress level, personality disorders, endogenous depression, and reduced self-rated health predict worse depression outcomes. Future research may examine the moderating effects of baseline depression severity and identify other clinical or demographic moderators.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.