Evidence map›Paper›PMID 21534999›Full record

ReviewAnnals of the New York Academy of Sciences2011

How do barrels form in somatosensory cortex?

Hong Li, Michael C Crair

Open access · greenAbstract readReview
In one paragraph

Review in Annals of the New York Academy of Sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Gestational Chlorpyrifos Exposure Imparts Lasting Alterations to the Rat Somatosensory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Activity-Dependent Synapse Refinement: From Mechanisms to Molecules.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. An insular view of the social decision-making network.Neuroscience and biobehavioral reviews · 2019
    Review
  15. Article
  16. Article
  17. Shaping Diversity Into the Brain's Form and Function.Frontiers in neural circuits · 2018
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hong LiDepartment of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, USA.
Michael C Crair
Yale University · US

Funding

DEVELOPMENT AND PLASTICITY AT THALAMOCORTICAL SYNAPSESR01MH062639 · NIMH · YALE UNIVERSITY · PI CRAIR, MICHAEL C. · 2001 to 2011
$3.1M
NIMH NIH HHS R01 MH062639
6 · The paper itself

Abstract

The somatosensory cortex of many rodents, lagomorphs, and marsupials contains distinct cytoarchitectonic features named "barrels" that reflect the pattern of large facial whiskers on the snout. Barrels are composed of clustered thalamocortical afferents relaying sensory information from one whisker surrounded by cell-dense walls or "barrels" in layer 4 of the cortex. In many ways, barrels are a simple and relatively accessible canonical cortical column, making them a common model system for the examination of cortical development and function. Despite their experimental accessibility and popularity, we still lack a basic understanding of how and why barrels form in the first place. In this review, we will examine what is known about mechanisms of barrel development, focusing specifically on the recent literature using the molecular-genetic power of mice as a model system for examining brain development.

Indexed as

AnimalsBody PatterningHair FollicleMiceModels, BiologicalOrgan SpecificitySomatosensory CortexVibrissae

Identifiers

PMID21534999
PMCPMC4700879
OpenAlexW2096272575

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.