Evidence map›Paper›PMID 21534090›Full record

ArticleJournal of toxicology and environmental health. Part B, Critical reviews2011

Factors that impact susceptibility to fiber-induced health effects.

Jennifer E Below, Nancy J Cox, Naomi K Fukagawa, Ari Hirvonen, Joseph R Testa

Open access · bronzeAbstract read
In one paragraph

Article in Journal of toxicology and environmental health. Part B, Critical reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Mortality from asbestos-associated disease in Libby, Montana 1979-2011.Journal of exposure science & environmental epidemiology · 2017
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jennifer E BelowDepartment of Medicine, Section of Genetic Medicine, University of Chicago, Chicago, Illinois 60637, USA. below@uchicago.edu
Nancy J Cox
Naomi K Fukagawa
Ari Hirvonen
Joseph R Testa
University of Chicago · USFinnish Institute of Occupational Health · FIFox Chase Cancer Center · USUniversity of Vermont · US

Funding

PREDOCTORAL TRAINING IN GENETICS AND REGULATIONT32GM007197 · NIGMS · UNIVERSITY OF CHICAGO · PI ROTHMAN-DENES, LUCIA B. B · 1985 to 2020
$17.0M
6 · The paper itself

Abstract

Asbestos and related fibers are associated with a number of adverse health effects, including malignant mesothelioma (MM), an aggressive cancer that generally develops in the surface serosal cells of the pleural, pericardial, and peritoneal cavities. Although approximately 80% of individuals with MM are exposed to asbestos, fewer than 5% of asbestos workers develop MM. In addition to asbestos, other mineralogical, environmental, genetic, and possibly viral factors might contribute to MM susceptibility. Given this complex etiology of MM, understanding susceptibility to MM needs to be a priority for investigators in order to reduce exposure of those most at risk to known environmental carcinogens. In this review, the current body of literature related to fiber-associated disease susceptibility including age, sex, nutrition, genetics, asbestos, and other mineral exposure is addressed with a focus on MM, and critical areas for further study are recommended.

Indexed as

Age FactorsAnimalsAsbestosCarcinogens, EnvironmentalChromosome AberrationsCocarcinogenesisDisease SusceptibilityEnvironmental PollutantsGenetic Predisposition to DiseaseHumansMesotheliomaMineral FibersNutritional StatusRadiation EffectsRiskSex CharacteristicsAsbestosCarcinogens, EnvironmentalEnvironmental PollutantserioniteMineral FibersZeolites

Identifiers

PMID21534090
PMCPMC3118508
OpenAlexW2059981766

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.