Evidence map›Paper›PMID 21534087›Full record

ReviewJournal of toxicology and environmental health. Part B, Critical reviews2011

Nonpulmonary outcomes of asbestos exposure.

Melisa Bunderson-Schelvan, Jean C Pfau, Robert Crouch, Andrij Holian

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of toxicology and environmental health. Part B, Critical reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Autoantibodies and cancer among asbestos-exposed cohorts in Western Australia.Journal of toxicology and environmental health. Part A · 2021
    Article
  9. Article
  10. Mechanisms of Environment-Induced Autoimmunity.Annual review of pharmacology and toxicology · 2021
    Article
  11. Article
  12. Asbestos exposure and autoantibody titers.Annals of occupational and environmental medicine · 2020
    Article
  13. Review
  14. Risk assessment of gastric cancer associated with asbestosis: a case report.Annals of occupational and environmental medicine · 2015
    Article
  15. Article
  16. Autoimmunity and asbestos exposure.Autoimmune diseases · 2014
    Review
  17. Asbestos-Induced Gastrointestinal Cancer: An Update.Journal of gastrointestinal & digestive system · 2013
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Melisa Bunderson-SchelvanCenter for Environmental Health Sciences, Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana 59801, USA. melisa.schelvan@umontana.edu
Jean C Pfau
Robert Crouch
Andrij Holian
Idaho State University · USCenter for Environmental Health · USUniversity of Montana · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The adverse pulmonary effects of asbestos are well accepted in scientific circles. However, the extrapulmonary consequences of asbestos exposure are not as clearly defined. In this review the potential for asbestos to produce diseases of the peritoneum, immune, gastrointestinal (GIT), and reproductive systems are explored as evidenced in published, peer-reviewed literature. Several hundred epidemiological, in vivo, and in vitro publications analyzing the extrapulmonary effects of asbestos were used as sources to arrive at the conclusions and to establish areas needing further study. In order to be considered, each study had to monitor extrapulmonary outcomes following exposure to asbestos. The literature supports a strong association between asbestos exposure and peritoneal neoplasms. Correlations between asbestos exposure and immune-related disease are less conclusive; nevertheless, it was concluded from the combined autoimmune studies that there is a possibility for a higher-than-expected risk of systemic autoimmune disease among asbestos-exposed populations. In general, the GIT effects of asbestos exposure appear to be minimal, with the most likely outcome being development of stomach cancer. However, IARC recently concluded the evidence to support asbestos-induced stomach cancer to be "limited." The strongest evidence for reproductive disease due to asbestos is in regard to ovarian cancer. Unfortunately, effects on fertility and the developing fetus are under-studied. The possibility of other asbestos-induced health effects does exist. These include brain-related tumors, blood disorders due to the mutagenic and hemolytic properties of asbestos, and peritoneal fibrosis. It is clear from the literature that the adverse properties of asbestos are not confined to the pulmonary system.

Indexed as

AnimalsAsbestosAsbestosisAutoimmune DiseasesCarcinogens, EnvironmentalEnvironmental PollutantsFemaleFetal DevelopmentGastrointestinal NeoplasmsHumansMaleNeoplasms, MesothelialUrogenital NeoplasmsAsbestosCarcinogens, EnvironmentalEnvironmental Pollutants

Identifiers

PMID21534087
PMCPMC3118539
OpenAlexW2027783701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.