Evidence map›Paper›PMID 21533987›Full record

ArticleChromosoma2011

Molecular and cytological characterization of repetitive DNA sequences from the centromeric heterochromatin of Sciara coprophila.

M Carmen Escribá, Patricia G Greciano, María Méndez-Lago, Beatriz de Pablos, Vladimir A Trifonov, Malcolm A Ferguson-Smith, Clara Goday, Alfredo Villasante

Abstract read
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In one paragraph

Article in Chromosoma, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. The enigma of the B chromosome-specific behaviour.Frontiers in plant science · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Insects · 2024
    Article
  6. Non-random chromosome segregation and chromosome eliminations in the fly Bradysia (Sciara).Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

M Carmen EscribáCentro de Biología Molecular "Severo Ochoa" (CSIC-UAM), Universidad Autónoma de Madrid, Nicolás Cabrera, Spain.
Patricia G Greciano
María Méndez-Lago
Beatriz de Pablos
Vladimir A Trifonov
Malcolm A Ferguson-Smith
Clara Goday
Alfredo Villasante
Universidad Autónoma de Madrid · ESCentro de Biología Molecular Severo Ochoa · ESCentro de Investigaciones Biológicas Margarita Salas · ESGenomics (United Kingdom) · GBSiberian Branch of the Russian Academy of Sciences · RUUniversity of Chicago · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

Sciara coprophila (Diptera, Nematocera) constitutes a classic model to analyze unusual chromosome behavior such as the somatic elimination of paternal X chromosomes, the elimination of the whole paternal, plus non-disjunction of the maternal X chromosome at male meiosis. The molecular organization of the heterochromatin in S. coprophila is mostly unknown except for the ribosomal DNA located in the X chromosome pericentromeric heterochromatin. The characterization of the centromeric regions, thus, is an essential and required step for the establishment of S. coprophila as a model system to study fundamental mechanisms of chromosome segregation. To accomplish such a study, heterochromatic sections of the X chromosome centromeric region from salivary glands polytene chromosomes were microdissected and microcloned. Here, we report the identification and characterization of two tandem repeated DNA sequences from the pericentromeric region of the X chromosome, a pericentromeric RTE element and an AT-rich centromeric satellite. These sequences will be important tools for the cloning of S. coprophila centromeric heterochromatin using libraries of large genomic clones.

Indexed as

AnimalsCentromereChromosome MappingDipteraDNAHeterochromatinIn Situ Hybridization, FluorescenceLarvaMaleMeiosisMolecular Sequence DataPhylogenyPolytene ChromosomesSalivary GlandsTandem Repeat SequencesTissue FixationDNAHeterochromatin

Identifiers

PMID21533987
OpenAlexW2001607718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.