Evidence map›Paper›PMID 21533520›Full record

ArticleSurgical endoscopy2011

Endoscopic findings and outcomes of revisional procedures for patients with weight recidivism after gastric bypass.

Panot Yimcharoen, Helen M Heneghan, Manish Singh, Stacy Brethauer, Philip Schauer, Tomasz Rogula, Matthew Kroh, Bipan Chand

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01871896 (Apollo OverStitch for Bariatric Surgery Revision After Weight Loss Failure), which is not on this map. Cited by 51 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 9 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01871896 nacompletednot on this mapstarted 2014, after this paper: background citation

Apollo OverStitch for Bariatric Surgery Revision After Weight Loss Failure

TypeinterventionalSponsorUniversity of California, San FranciscoRan2014 to 2022Enrolled24ConditionsMorbid Obesity, Weight LossArmsEndoscopic Suturing to Create Early Satiety
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 9 syntheses or guidelines pooled it, 134 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Panot YimcharoenBariatric and Metabolic Institute, Cleveland Clinic, Cleveland, OH 44195, USA. yimchap@ccf.org
Helen M Heneghan
Manish Singh
Stacy Brethauer
Philip Schauer
Tomasz Rogula
Matthew Kroh
Bipan Chand
Cleveland Clinic · USAmerican Society for Metabolic and Bariatric Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSignificant weight regain occurs for 10% to 20% of patients after Roux-en-Y gastric bypass (RYGB). Potential causative factors include anatomic abnormalities such as enlargement of the gastric pouch and gastrojejunostomy (GJ). This report describes endoscopic findings for patients referred for investigation of weight regain and presents the outcomes of revisional therapy for patients with abnormal anatomy.

methodsTo evaluate gastric pouch and stoma size, RYGB patients referred for weight regain underwent upper endoscopy. A GJ was defined as enlarged if it had a diameter greater than 2 cm in any dimension, and a pouch was defined as enlarged if its length exceeded 6 cm long or its width exceeded 5 cm. Patients with abnormal anatomy who subsequently underwent revisional procedures were arbitrarily categorized into three groups based on the interval from RYGB to endoscopic evaluation: less than 5 years (group 1), 5 to 10 years (group 2), longer than 10 years (group 3). The percentage of regained weight lost (%RWL) after revision was compared between the groups.

resultsIn this study, 205 RYGB patients (176 women with a mean age of 47 ± 10 years and a current body mass index [BMI] of 43.4 ± 8.4 kg/m(2)) were evaluated. The mean time from primary RYGB was 6.9 ± 3.7 years, and the increase in BMI from its nadir was 9.78 ± 5.80 kg/m(2). Abnormal endoscopic findings (n = 146, 71.2%) included large GJ (n = 86, 58.9%), large pouch (n = 42, 28.8%), or both (n = 18, 12.3%). Of the 205 patients, 51 (24.9%) underwent a revisional surgical or endoluminal procedure. At a mean follow-up assessment 13 months after revision, group 1 (n = 12) had a mean %RWL of 103% ± 89.3%, and 62% of these patients lost all their regained weight. The mean %RWL was 45% ± 12.6% in group 2 (n = 30) and 40% ± 13.6% in group 3 (n = 9).

conclusionEndoscopy is a valuable tool for evaluating weight regain after bariatric surgery that can identify abnormal post-RYGB anatomy in a majority of patients. Revisional procedures to restore normal RYGB anatomy appear to be most successful if performed within 5 years after the primary procedure.

Indexed as

Endoscopy, GastrointestinalAnalysis of VarianceAnastomosis, Roux-en-YBody Mass IndexChi-Square DistributionFemaleGastric BypassHumansMaleMiddle AgedObesity, MorbidRecurrenceReoperationStatistics, NonparametricTreatment OutcomeWeight Gain

Identifiers

PMID21533520
OpenAlexW2047318130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.