ArticleEuropean journal of clinical pharmacology2011
Antiepileptic drug use in community-dwelling and institutionalized elderly: a nationwide study of over 1,300,000 older people.
Article in European journal of clinical pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 48 citations in OpenAlex.
- Identifying determinants for falls among Iranian older adults: insights from the Bushehr Elderly Health Program.BMC geriatrics · 2024Article
- Antiseizure medications for post-stroke epilepsy: A real-world prospective cohort study.Brain and behavior · 2021Article
- Fall predictors beyond fall risk assessment tool items for acute hospitalized older adults: a matched case-control study.Scientific reports · 2021Article
- PRN Medicines Management for Older People with Long-Term Mental Health Disorders in Home Care.Risk management and healthcare policy · 2021Review
- Patterns of anticonvulsant use and adverse drug events in older adults.Pharmacoepidemiology and drug safety · 2021Article
- The Prevalence and Factors Associated with Antiepileptic Drug Use in US Nursing Home Residents.Drugs & aging · 2020Article
- Use of Central Nervous System (CNS) Medicines in Aged Care Homes: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2019Article
- Poststroke epilepsy: current perspectives on diagnosis and treatment.Neuropsychiatric disease and treatment · 2019Review
- Antiepileptic Drug Use Is Associated with an Increased Risk of Pneumonia Among Community-Dwelling Persons with Alzheimer's Disease-Matched Cohort Study.Journal of Alzheimer's disease : JAD · 2019Article
- Antiepileptic Drug Use and the Risk of Stroke Among Community-Dwelling People With Alzheimer Disease: A Matched Cohort Study.Journal of the American Heart Association · 2018Article
- Incidence and Prevalence of Antiepileptic Medication Use in Community-Dwelling Persons with and without Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2018Article
- Medication Regimen Complexity and Number of Medications as Factors Associated With Unplanned Hospitalizations in Older People: A Population-based Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016Article
- Use of Fall-Risk Inducing Drugs in Patients Using Anti-Parkinson Drugs (APD): A Swedish Register-Based Study.PloS one · 2016Article
- Prevalence of Different Combinations of Antiepileptic Drugs and CNS Drugs in Elderly Home Care Service and Nursing Home Patients in Norway.Epilepsy research and treatment · 2016Article
- Factors associated with medication regimen complexity in older people: a cross-sectional population-based study.European journal of clinical pharmacology · 2015Article
- Potentially inappropriate drug use in older people: a nationwide comparison of different explicit criteria for population-based estimates.British journal of clinical pharmacology · 2015Article
- Socioeconomic inequalities in access to specialized psychotropic prescribing among older Swedes: a register-based study.European journal of public health · 2014Article
- Sources of European drug consumption data at a country level.International journal of public health · 2014Article
- Article
- Different patterns in use of antibiotics for lower urinary tract infection in institutionalized and home-dwelling elderly: a register-based study.European journal of clinical pharmacology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate whether institutionalization is associated with the use of antiepileptic drugs (AEDs) and to compare the association between use of AEDs and psychotropics in community-dwelling and institutionalized elderly, after adjustment for age, sex and co-morbidity (i.e. number of other drugs).
methodsWe analyzed data on age, sex and dispensed drugs for individuals aged ≥65 years registered in the Swedish Prescribed Drug Register from July to September 2008, record-linked to the Swedish Social Services Register (n = 1,345,273: 1,258,565 community-dwelling and 86 708 institutionalized elderly). Multivariate logistic regression analysis was used to analyze whether institutionalization and use of psychotropics (i.e. antipsychotics, anxiolytics, hypnotics/sedatives and antidepressants) were associated with the use of AEDs.
resultsAEDs were used by 2% of the community-dwelling and 9% of the institutionalized elderly. The most commonly used AEDs were carbamazepine, gabapentin, pregabalin, valproic acid and lamotrigine. Institutionalization was strongly associated with AED use (OR(adjusted) = 3.98; 95% CI 3.86-4.10). In community-dwelling elderly, AED use was associated with an increased probability of use of all types of psychotropics. However, among institutionalized elderly, the associations between use of AEDs and psychotropics showed a mixed pattern.
conclusionsAED use seems to be common among Swedish institutionalized elderly, and institutionalization is a strong determinant of AED use. Our results may also indicate an off-label prescribing of AEDs as an alternative to psychotropics in the institutional setting. This finding needs to be confirmed by others and evaluated with respect to outcomes of this treatment in institutionalized elderly.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.