Evidence map›Paper›PMID 21532972›Full record

ArticleJournal of addiction medicine2011

How do prescription opioid users differ from users of heroin or other drugs in psychopathology: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

Li-Tzy Wu, George E Woody, Chongming Yang, Dan G Blazer

Open access · greenAbstract read
In one paragraph

Article in Journal of addiction medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 4 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 4 syntheses or guidelines pooled it, 108 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Li-Tzy WuDepartment of Psychiatry and Behavioral Sciences, School of Medicine, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA. litzy.wu@duke.edu
George E Woody
Chongming Yang
Dan G Blazer
Duke Medical Center · US

Funding

Delaware Valley Node of the Clinical Trials NetworkU10DA013043 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI WOODY, GEORGE EDWARD · 1999 to 2015
$25.8M
Evolution of Psychopathology in the PopulationR01DA026652 · NIDA · JOHNS HOPKINS UNIVERSITY · PI EATON, WILLIAM W · 2009 to 2013
$2.4M
Treatment/Substance Use Disorders/HIV Risk ReductionK05DA017009 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI WOODY, GEORGE EDWARD · 2003 to 2012
$1.3M
MDMA and Other Hallucinogen Use: Onset and Abuse/DependenceR01DA019623 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2007 to 2013
$1.1M
Classification of Substance Use Severity and Treatment Outcomes: NIDA CTN StudiesR33DA027503 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2010 to 2012
$1.1M
Epdemiology of Non-Medical Prescription Anagesic UseR01DA019901 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2007 to 2009
$416k
Classification of Substance Use Severity and Treatment Outcomes: NIDA CTN StudiesR21DA027503 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2009 to 2009
$302k
NIDA NIH HHS DA013043NIDA NIH HHS DA017009NIDA NIH HHS DA0196623NIDA NIH HHS DA019901NIDA NIH HHS DA026652NIDA NIH HHS DA027503NIDA NIH HHS HHSN271200522071CNIDA NIH HHS K05 DA017009NIDA NIH HHS R01 DA019623NIDA NIH HHS R01 DA019901NIDA NIH HHS R01 DA026652NIDA NIH HHS R21 DA027503NIDA NIH HHS R33 DA027503NIDA NIH HHS U10 DA013043
6 · The paper itself

Abstract

objectivesTo study substance use and psychiatric disorders among prescription opioid users, heroin users, and non-opioid drug users in a national sample of adults.

methodsAnalyses of data from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (N=43,093).

resultsFour groups were identified among 9140 illicit or non-prescribed drug users: heroin-other opioid users (1.0%; used heroin and other opioids), other opioid-only users (19.8%; used other opioids but never heroin), heroin-only users (0.5%; used heroin but never other opioids), and non-opioid drug users (78.7%; used drugs but never heroin or other opioids). After adjusting for variations in socioeconomic characteristics, history of substance abuse treatment, and familial substance abuse, heroin-other opioid users had greater odds of several substance use disorders (cocaine, hallucinogen, sedative, amphetamine, and tranquilizer) as compared with the other groups; heroin-only users had reduced odds of sedative and tranquilizer use disorders as compared with other opioid-only users. Non-opioid drug users had reduced odds of all substance use disorders and other mental disorders (mood, anxiety, pathological gambling, and personality) as compared with other opioid-only users. Past-year other opioid-only users also reported slightly lower scores on quality of life than past-year non-opioid drug users.

conclusionsAll opioid use groups had higher rates of substance use disorders than non-opioid drug users, and these rates were particularly elevated among heroin-other opioid users. Findings suggest the need to distinguish between these four groups in research and treatment as they may have different natural histories and treatment needs.

Indexed as

Illicit DrugsAdolescentAdultAnxiety DisordersComorbidityCross-Sectional StudiesFemaleHealth SurveysHeroin DependenceHumansInterview, PsychologicalMaleMental DisordersMiddle AgedMood DisordersNarcoticsIllicit DrugsNarcoticsComorbidityHeroin use disordersOpioid use disordersPrescription opioid abuse

Identifiers

PMID21532972
PMCPMC3082206
OpenAlexW1984416965

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.