Evidence map›Paper›PMID 21532964›Full record

ArticlePregnancy hypertension2011

The Role of Obesity in Preeclampsia.

James M Roberts, Lisa M Bodnar, Thelma E Patrick, Robert W Powers

2 registry-linked trialsAbstract read
In one paragraph

Article in Pregnancy hypertension, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 93 papers.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05533996 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Body Fat Index as a Novel Sonographic Tool to Predict High Risk Pregnancy (BFiORS Trial)

TypeinterventionalSponsorAssiut UniversityRan2023 to 2024Enrolled206ConditionsGestational Diabetes, Pre-Eclampsia, Labour DystociaArmsultrasound
NCT05840497 narecruitingnot on this mapstarted 2023, after this paper: background citation

Efecto Del Ejercicio De Fuerza-resistencia En La Disminución De La Diabetes Gestacional En Gestantes Con Sobrepeso U Obesidad

TypeinterventionalSponsorFundacion Miguel ServetRan2023 to 2025Enrolled200ConditionsDiabetes, GestationalArmsResistance exercise
3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 195 citations in OpenAlex.

  1. Article
  2. Article
  3. Maternal Obesity Doubles the Risk of Preeclampsia and Eclampsia: Post-COVID Changes in a Brazilian Cohort of 2.3 Million Hospitalizations.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. The Roles of Obesity and ASB4 in Preeclampsia Pathogenesis.International journal of molecular sciences · 2024
    Review
  19. Article
  20. Article

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

James M RobertsMagee-Womens Research Institute, University of Pittsburgh.
Lisa M Bodnar
Thelma E Patrick
Robert W Powers
Magee-Womens Research Institute · USUniversity of Pittsburgh · US

Funding

TROPHOBLAST PRODUCTS IN GENESIS OF PREECLAMPSIAP01HD030367 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI HUBEL, CARL A · 1993 to 2012
$17.2M
NICHD NIH HHS P01 HD030367
6 · The paper itself

Abstract

The incidence of obesity is increasing at an alarming rate. There is compelling evidence that obesity increases the risk of preeclampsia about 3-fold, and in developed countries is the leading attributable risk for the disorder. In this presentation we explore this relationship and propose targets for future studies guided by the much more extensively studied relationship of obesity to cardiovascular disease. We further address the hypothesis that asymmetric dimethyl arginine (ADMA), an endogenous inhibitor of nitric oxide synthase, may be one convergence point for the mechanism by which obesity increases the risk of preeclampsia. We conclude with consideration of the clinical implications of this information.

Identifiers

PMID21532964
PMCPMC3082136
OpenAlexW2014737092

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.