ArticleJournal of Korean medical science2011
Helicobacter pylori infection is associated with elevated low density lipoprotein cholesterol levels in elderly Koreans.
Article in Journal of Korean medical science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The effect of Hp infection on dyslipidemia in Asia and out of Asia: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Helicobacter pylori infection contributes to high risk of ischemic stroke: evidence from a meta-analysis.Journal of neurology · 2012Pooled it
- Association of Helicobacter pylori infection with elevated low-density lipoprotein cholesterol and fasting glucose: a large-scale analysis of 83,054 participants in central China.BMC infectious diseases · 2026Article
- Glucolipid Metabolic Disorders andInternational journal of endocrinology · 2026Review
- Histopathologic Findings in Sleeve Gastrectomy Specimens: Is Routine Pathological Examination Always Necessary?Iranian journal of pathology · 2026Article
- Gut-Heart Axis: Microbiome Involvement in Restrictive Cardiomyopathies.Biomedicines · 2025Review
- Association of lifestyle change after H. pylori eradication with cardiovascular disease: a nationwide Korean NHIS cohort study.BMJ public health · 2025Article
- Causal associations between intermediate very-low-density lipoprotein cholesterol-to-total lipids ratio and peptic ulcer: A bidirectional Mendelian randomization study.World journal of clinical cases · 2024Article
- Traditional and nontraditional lipid parameters inBiomarkers in medicine · 2024Article
- Article
- Metabolic syndrome and associated factors amongFrontiers in endocrinology · 2024Article
- Long-term Helicobacter pylori infection is associated with an increased risk of carotid plaque formation: a retrospective cohort study.Frontiers in cardiovascular medicine · 2024Article
- Article
- Evaluation of a Comprehensive Profile of Salivary Analytes for the Diagnosis of the Equine Gastric Ulcer Syndrome.Animals : an open access journal from MDPI · 2022Article
- The association ofHeliyon · 2022Article
- Dyslipidemia and Its Associated Factors AmongJournal of multidisciplinary healthcare · 2022Article
- No evidence for a causal link betweenFrontiers in microbiology · 2022Article
- Evaluation of Lipid Profile and Inflammatory Marker in Patients with GastricInternational journal of general medicine · 2022Article
- Nationwide cohort study: cholesterol level is inversely related with the risk of gastric cancer among postmenopausal women.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2022Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was conducted to investigate the association between Helicobacter pylori (H. pylori) infection and the lipid profile among elderly Koreans. A total of 462 subjects (mean age 66.2 ± 7.6 yr, 84% males) who underwent health check-up were investigated. Each subject underwent gastroduodenoscopy with gastric mucosal biopsy, and H. pylori infection was determined by histopathological examination using the updated Sydney System score. The presence of H. pylori infection was significantly associated with the elevated serum levels of total cholesterol and low density lipoprotein (LDL) cholesterol (P < 0.05 for each) in univariate analysis. H. pylori infection was not associated with triglyceride and high density lipoprotein (HDL) cholesterol levels (P > 0.05 for each). After controlling confounders, multiple logistic regression analysis showed that the odds ratio of H. pylori infection for high LDL cholesterol level (> 140 mg/dL) was 3.113 (95% confidence interval, 1.364-7.018; P = 0.007). There were no significant associations between the presence of H. pylori infection and elevated total cholesterol levels (> 200 mg/dL) in this model (P = 0.586). The results of this study demonstrate that H. pylori infection is associated with the elevated serum LDL cholesterol levels in elderly Koreans, supporting the hypothesis that H. pylori plays a role in promoting atherosclerosis by modifying lipid metabolism.
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