Evidence map›Paper›PMID 21532557›Full record

ArticleNature reviews. Drug discovery2011

Belimumab.

Iñaki Sanz, Uma Yasothan, Peter Kirkpatrick

Abstract readNews
PubMed Publisher
In one paragraph

Article in Nature reviews. Drug discovery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Clinical translation of immunomodulatory therapeutics.Advanced drug delivery reviews · 2021
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. The Expression of BAFF Is Controlled by IRF Transcription Factors.Journal of immunology (Baltimore, Md. : 1950) · 2016
    Article
  13. Review
  14. B-cell-depleting therapy in systemic lupus erythematosus.The American journal of medicine · 2012
    Review
  15. New treatment options for lupus - a focus on belimumab.Therapeutics and clinical risk management · 2012
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Iñaki Sanz
Uma Yasothan
Peter Kirkpatrick

Funding

Role of B Cells in Synovial Inflammation & LN Remodeling in RA ArthritisP01AI078907 · NIAID · UNIVERSITY OF ROCHESTER · PI ANOLIK, JENNIFER HOWITT · 2010 to 2014
$10.8M
Translational Research Project Effector and Regulatory B cells in SLEU19AI056390 · NIAID · UNIVERSITY OF ROCHESTER · PI SANZ, IGNACIO E. · 2003 to 2013
$8.9M
A Model System for the Study of Human B-cell ToleranceR37AI049660 · NIAID · UNIVERSITY OF ROCHESTER · PI SANZ, IGNACIO E. · 2010 to 2019
$3.7M
NIAID NIH HHS P01 AI078907NIAID NIH HHS R37 AI049660NIAID NIH HHS U19 AI056390
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedB-Cell Activating FactorDrug ApprovalHumansLupus Erythematosus, SystemicUnited StatesUnited States Food and Drug AdministrationAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedB-Cell Activating Factorbelimumab

Identifiers

PMID21532557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.