ArticleMolecular biology and evolution2011
Genome reduction by deletion of paralogs in the marine cyanobacterium Prochlorococcus.
Article in Molecular biology and evolution, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 58 citations in OpenAlex.
- Ecosystem relocation on Snowball Earth: Polar-alpine ancestry of the extant surface biosphere?Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Massive genome reduction predates the divergence of Symbiodiniaceae dinoflagellates.The ISME journal · 2024Article
- Genome reduction occurred in early Prochlorococcus with an unusually low effective population size.The ISME journal · 2024Article
- Review
- Exploring the Diversity of the Thioredoxin Systems in Cyanobacteria.Antioxidants (Basel, Switzerland) · 2022Review
- Prochlorococcus have low global mutation rate and small effective population size.Nature ecology & evolution · 2022Article
- Impact of Genome Reduction in Microsporidia.Experientia supplementum (2012) · 2022Article
- Mechanisms driving genome reduction of a novel Roseobacter lineage.The ISME journal · 2021Article
- Snowball Earth, population bottleneck andProceedings. Biological sciences · 2021Article
- Unexpectedly high mutation rate of a deep-sea hyperthermophilic anaerobic archaeon.The ISME journal · 2021Article
- Synergism between the Black Queen effect and the proteomic constraint on genome size reduction in the photosynthetic picoeukaryotes.Scientific reports · 2020Article
- Comprehensive dissection of dispensable genomic regions in Streptomyces based on comparative analysis approach.Microbial cell factories · 2020Article
- Insights Into the Evolution of Picocyanobacteria and Phycoerythrin Genes (Frontiers in microbiology · 2019Article
- Genome Rearrangement Shapes Prochlorococcus Ecological Adaptation.Applied and environmental microbiology · 2018Article
- Comparative Genomics Reveals Evidence of Genome Reduction and High Extracellular Protein Degradation Potential inFrontiers in microbiology · 2018Article
- Trajectories and Drivers of Genome Evolution in Surface-Associated Marine Phaeobacter.Genome biology and evolution · 2017Article
- Excess of non-conservative amino acid changes in marine bacterioplankton lineages with reduced genomes.Nature microbiology · 2017Article
- Endosymbiont evolution: predictions from theory and surprises from genomes.Annals of the New York Academy of Sciences · 2015Review
- Evolutionary origin of a streamlined marine bacterioplankton lineage.The ISME journal · 2015Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Several isolates of the marine cyanobacterial genus Prochlorococcus have smaller genome sizes than those of the closely related genus Synechococcus. In order to test whether loss of protein-coding genes has contributed to genome size reduction in Prochlorococcus, we reconstructed events of gene family evolution over a strongly supported phylogeny of 12 Prochlorococcus genomes and 9 Synechococcus genomes. Significantly, more events both of loss of paralogs within gene families and of loss of entire gene families occurred in Prochlorococcus than in Synechococcus. The number of nonancestral gene families in genomes of both genera was positively correlated with the extent of genomic islands (GIs), consistent with the hypothesis that horizontal gene transfer (HGT) is associated with GIs. However, even when only isolates with comparable extents of GIs were compared, significantly more events of gene family loss and of paralog loss were seen in Prochlorococcus than in Synechococcus, implying that HGT is not the primary reason for the genome size difference between the two genera.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.