Evidence map›Paper›PMID 21527896›Full record

Trial reportObesity (Silver Spring, Md.)2012

Predictors of long-term weight loss in adults with modest initial weight loss, by sex and race.

Laura P Svetkey, Jamy D Ard, Victor J Stevens, Catherine M Loria, Deb Y Young, Jack F Hollis, Lawrence J Appel, Phillip J Brantley, Betty M Kennedy, Shiriki K Kumanyika and 5 more

Abstract readClinical Trial, Phase IClinical Trial, Phase IIMulticenter Study
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 4 pooled it
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 4 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
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  3. Determinants of weight loss maintenance: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2019
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  19. SisterTalk: final results of a culturally tailored cable television delivered weight control program for Black women.The international journal of behavioral nutrition and physical activity · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

Laura P SvetkeySarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, USA. svetk001@mc.duke.edu
Jamy D Ard
Victor J Stevens
Catherine M Loria
Deb Y Young
Jack F Hollis
Lawrence J Appel
Phillip J Brantley
Betty M Kennedy
Shiriki K Kumanyika
Bryan C Batch
Leonor Corsino
Lillian F Lien
William M Vollmer
Weight Loss Maintenance Collaborative Research Group
Duke Medical Center · USKaiser Permanente Center for Health Research · USDuke University · USJohns Hopkins University · USNational Heart Lung and Blood Institute · USOrleans Parish School Board · USPennington Biomedical Research Center · USUniversity of Alabama at Birmingham · USUniversity of Maryland, College Park · USUniversity of Pennsylvania · US

Funding

WEIGHT LOSS MAINTENANCE TRIALU01HL068676 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI STEVENS, VICTOR J · 2003 to 2009
$7.4M
WEIGHT LOSS MAINTENANCE TRIALU01HL068734 · NHLBI · DUKE UNIVERSITY · PI SVETKEY, LAURA P · 2003 to 2007
$3.1M
WEIGHT LOSS MAINTENANCE TRIALU01HL068790 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI HOLLIS, JACK F · 2003 to 2007
$2.4M
WEIGHT LOSS MAINTENANCE TRIALU01HL068920 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI APPEL, LAWRENCE JOHN · 2003 to 2007
$2.4M
WEIGHT LOSS MAINTENANCE TRIALU01HL068955 · NHLBI · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BRANTLEY, PHILLIP J · 2003 to 2007
$2.3M
NHLBI NIH HHS 5-HL68955NHLBI NIH HHS 5-U01 HL68676NHLBI NIH HHS 5-U01 HL68734NHLBI NIH HHS 5-U01 HL68790NHLBI NIH HHS 5-U01 HL68920NHLBI NIH HHS U01 HL068676NHLBI NIH HHS U01 HL068734NHLBI NIH HHS U01 HL068790NHLBI NIH HHS U01 HL068920NHLBI NIH HHS U01 HL068955
6 · The paper itself

Abstract

Effective weight management interventions could reduce race-sex disparities in cardiovascular disease (CVD), yet little is known about factors associated with successful weight loss maintenance in race-sex subgroups. In the Weight Loss Maintenance trial (WLM), overweight/obese (BMI 25-45 kg/m(2)) adults who lost ≥4 kg in a 6-month behavioral weight loss intervention (phase I) were randomized into one of three 30-month maintenance interventions (phase II). To investigate predictors in subgroups, randomized groups were combined for this analysis. Of 1,685 phase I participants, 1,032 (61%) entered phase II, including 12% black men (BM), 26% black women (BW), 25% white men (WM), and 37% white women (WW). Weight change over the 36-month study ranged from -2.3% (95% confidence interval = -3.1 to -1.5%) in BW to -4.5% (95% confidence interval = -5.7 to -4.0%) in WM, the result of differential weight loss during phase I. Within race, men lost significantly more weight than women, but within sex group, weight loss did not differ significantly between races. Although participants regained weight during phase II, regain did not differ by race-sex group, and mean weight at the end of the study was significantly lower than phase I entry weight for each subgroup. In regression models, phase I weight loss predicted overall 36-month weight loss in all race-sex groups. Healthy dietary pattern at entry, improvement in dietary pattern, or both were predictive in three of four race-sex groups. Few other variables other than initial weight loss and dietary pattern were predictive. Future research should identify additional modifiable influences on long-term maintenance after a modest weight loss.

Indexed as

Weight LossBlack or African AmericanCardiovascular DiseasesDiabetes Mellitus, Type 2Diabetic AngiopathiesDiet RecordsFemaleHealth Status DisparitiesHispanic or LatinoHumansMaleMiddle AgedObesityPatient CompliancePredictive Value of TestsSex Factors

Identifiers

PMID21527896
PMCPMC3830958
OpenAlexW2016164324

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.