Evidence map›Paper›PMID 21527780›Full record

ArticleGenetics2011

A unified treatment of the probability of fixation when population size and the strength of selection change over time.

D Waxman

Abstract read
In one paragraph

Article in Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Fixation Probabilities of Mutant Alleles in an Ecological Context.bioRxiv : the preprint server for biology · 2026
    Article
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  9. Surfing on the seascape: Adaptation in a changing environment.Evolution; international journal of organic evolution · 2019
    Article
  10. Article
  11. Evolutionary justifications for human reproductive limitations.Journal of assisted reproduction and genetics · 2018
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

D WaxmanCentre for Computational Systems Biology, Fudan University, Shanghai 200433, People's Republic of China. dwaxman.biology@gmail.com

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fixation probability is determined when population size and selection change over time and differs from Kimura's result, with long-term implications for a population. It is found that changes in population size are not equivalent to the corresponding changes in selection and can result in less drift than anticipated.

Indexed as

Genetics, PopulationSelection, GeneticAlgorithmsAllelesAnimalsEvolution, MolecularHumansModels, GeneticPopulation DensityProbabilityTime Factors

Identifiers

PMID21527780
PMCPMC3176099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.