ArticleGenetics2011
Transcription initiation from within P elements generates hypomorphic mutations in Drosophila melanogaster.
Article in Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Genetic dissection of theMolecular biology of the cell · 2025Article
- Precise mapping of one classic and three novelmicroPublication biology · 2023Article
- No apparent role for the Wari insulator in transcriptional regulation of the endogenousmicroPublication biology · 2023Article
- Gene dosage effects of poly(A) track-engineered hypomorphs.Molecular therapy. Nucleic acids · 2021Article
- A region of SLBP outside the mRNA-processing domain is essential for deposition of histone mRNA into theJournal of cell science · 2021Article
- Rapid generation of hypomorphic mutations.Nature communications · 2017Article
- The Notch ligand E3 ligase, Mind Bomb1, regulates glutamate receptor localization in Drosophila.Molecular and cellular neurosciences · 2016Article
- A transposable element insertion confers xenobiotic resistance in Drosophila.PLoS genetics · 2014Article
- Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster.Methods (San Diego, Calif.) · 2014Review
- Disruption of the protein kinase N gene of drosophila melanogaster results in the recessive delorean allele (pkndln) with a negative impact on wing morphogenesis.G3 (Bethesda, Md.) · 2014Article
- Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development.PloS one · 2012Article
- A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors.The EMBO journal · 2011Article
- Article
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Authors and funding
2 authors.
Funding
Abstract
Numerous transposable element insertions in Drosophila melanogaster cause hypomorphic mutations. We report that transcription initiation within a region found in many P-element constructs provides an explanation for why some gene function is retained. We detected evidence of this transcription in four different types of P constructs, regardless of whether the insertion was in a coding exon, intron, 5' untranslated region, or upstream of the gene span.
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Registered trials
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