ArticlePhysical therapy2011
An obese body mass increases the adverse effects of HIV/AIDS on balance and gait.
Article in Physical therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Objective impairments of gait and balance in adults living with HIV-1 infection: a systematic review and meta-analysis of observational studies.BMC musculoskeletal disorders · 2017Pooled it
- Feasibility and Impact of a Yoga Intervention on Cognition, Physical Function, Physical Activity, and Affective Outcomes among People Living with HIV: A Randomized Controlled Pilot Trial.Journal of the International Association of Providers of AIDS CareTrial
- Adipose Tissue Dysfunction and Energy Balance Paradigms in People Living With HIV.Endocrine reviews · 2024Review
- Factors affecting quality of life in adults with HIV: A local cross-sectional study.The South African journal of physiotherapy · 2023Article
- Mobility Deviations in Adults With Human Immunodeficiency Virus: A Cross-Sectional Assessment Using Gait Analysis, Functional Performance, and Self-Report.Open forum infectious diseases · 2021Article
- Fall History and Associated Factors Among Adults Living With HIV-1 in the Cape Winelands, South Africa: An Exploratory Investigation.Open forum infectious diseases · 2019Article
- Evaluating the Feasibility and Impact of a Yoga Intervention on Cognition, Physical Function, Physical Activity, and Affective Outcomes in People Living With HIV: Protocol for a Randomized Pilot Trial.JMIR research protocols · 2019Article
- HIV/AIDS and an overweight body mass are associated with excessive intra-individual variability in response preparation.Journal of neurovirology · 2018Article
- The Fat of the Matter: Obesity and Visceral Adiposity in Treated HIV Infection.Current HIV/AIDS reports · 2017Review
- Geriatric syndromes: new frontiers in HIV and sarcopenia.AIDS (London, England) · 2017Review
- Reported health, lifestyle and clinical manifestations associated with HIV status in people from rural and urban communities in the Free State Province, South Africa.Southern African journal of HIV medicine · 2017Article
- Fall frequency and associated factors among men and women with or at risk for HIV infection.HIV medicine · 2016Article
- Fat Matters: Understanding the Role of Adipose Tissue in Health in HIV Infection.Current HIV/AIDS reports · 2016Review
- Functional impairment, disability, and frailty in adults aging with HIV-infection.Current HIV/AIDS reports · 2014Article
- Knee extension and flexion strength asymmetry in Human Immunodeficiency Virus positive subjects: a cross-sectional study.Brazilian journal of physical therapyArticle
- Gait Speed Decline Is Associated with Hemoglobin A1C, Neurocognitive Impairment, and Black Race in Persons with HIV.AIDS research and human retrovirusesObservational
Corrections and comments
- Commented on by
Authors and funding
3 authors.
Funding
Abstract
backgroundBalance and gait problems have been detected among patients with HIV/AIDS. The extent to which these problems are exacerbated by either frailty or obesity has not been examined. Objective The purpose of this study was to compare participants who differed in body mass and the presence or absence of HIV/AIDS.
designThis was a cross-sectional study.
methodsQuantitative measurements were obtained from 86 participants who were HIV-type 1 (HIV-1) seronegative and 121 participants who were seropositive divided into subgroups based on their body mass index (BMI <21, 21-29, or >29 kg/m(2)).
resultsParticipants who were seropositive were impaired relative to seronegative controls on several indices, including the limit of stability, sway amplitude and sway strategy, gait initiation time, and gait speed during a fast pace condition. Participants who were obese also exhibited impairments, which were evident during assessments of the limit of stability, nonpreferred leg stance time, sway strategy, normal and fast gait speed, fast gait initiation time, and 360-degree turn time. Importantly, the analysis revealed that participants with both attributes were more impaired than those with either or neither attribute: patients who were obese and seropositive were more impaired in fast gait initiation time and cadence, nonpreferred leg stance time, 360-degree turn time, and sway strategy scores. Limitations The validity of BMI as a measure of body mass can be challenged. In addition, the validity of chair rise time and 360-degree turn time as estimates of lower-extremity strength (force-generating capacity) can be argued.
conclusionsThe present findings have an obvious and unfortunate implication: as more patients who are HIV-1 seropositive join the seronegative community in becoming obese, the effects of obesity and their disease may summate and their risk for balance and gait problems may increase.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.