ReviewNeuroscience and biobehavioral reviews2011
Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood.
Review in Neuroscience and biobehavioral reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Association of Val158Met polymorphism in COMT gene with attention-deficit hyperactive disorder: An updated meta-analysis.Medicine · 2020Pooled it
- Role of COMT in ADHD: a systematic meta-analysis.Molecular neurobiology · 2014Pooled it
- An epistasis between dopaminergic and oxytocinergic systems confers risk of post-traumatic stress disorder in a traumatized Chinese cohort.Scientific reports · 2019Trial
- Driven by Dopamine: Genetic Insights into Motivation and Performance in Sports and Esports.Genes · 2026Review
- Mechanisms of Changma Xifeng tablet in alleviating Tourette syndrome via modulation of neurotransmitters, inflammatory responses, and metabolic pathways.Frontiers in psychiatry · 2026Article
- Dopamine in Sports: A Narrative Review on the Genetic and Epigenetic Factors Shaping Personality and Athletic Performance.International journal of molecular sciences · 2024Review
- Risk and Resilience Variants in the Retinoic Acid Metabolic and Developmental Pathways Associated with Risk of FASD Outcomes.Biomolecules · 2024Article
- Cumulative Dopamine Genetic Score predicts behavioral and electrophysiological correlates of response inhibition via interactions with task demand.Cognitive, affective & behavioral neuroscience · 2020Article
- Interaction Between Prematurity and the MAOA Gene on Mental Development in Children: A Longitudinal View.Frontiers in pediatrics · 2020Article
- AFrontiers in psychiatry · 2018Article
- Identifying new susceptibility genes on dopaminergic and serotonergic pathways for the framing effect in decision-making.Social cognitive and affective neuroscience · 2017Article
- Genetic Correlates of Spirituality/Religion and Depression: A Study in Offspring and Grandchildren at High and Low Familial Risk for Depression.Spirituality in clinical practice (Washington, D.C.) · 2017Article
- Beyond main effects of gene-sets: harsh parenting moderates the association between a dopamine gene-set and child externalizing behavior.Brain and behavior · 2016Article
- A neuroscience perspective on sexual risk behavior in adolescence and emerging adulthood.Development and psychopathology · 2016Article
- Dopamine pathway gene variants may modulate cognitive performance in the DHS - Mind Study.Brain and behavior · 2016Article
- Article
- Neuroimaging of the dopamine/reward system in adolescent drug use.CNS spectrums · 2015Review
- Tourette syndrome and comorbid ADHD: causes and consequences.European journal of pediatrics · 2015Review
- Differential effects of dopamine-directed treatments on cognition.Neuropsychiatric disease and treatment · 2015Review
- The neurobiological link between OCD and ADHD.Attention deficit and hyperactivity disorders · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Dopamine hypotheses of several psychiatric disorders are based upon the clinical benefits of drugs affecting dopamine transporter or receptors, and have prompted intensive candidate gene research within the dopaminergic system during the last two decades. The aim of this review is to survey the most important findings concerning dopaminergic gene polymorphisms in attention deficit hyperactivity disorder (ADHD), Tourette syndrome (TS), obsessive compulsive disorder, and substance abuse. Also, genetic findings of related phenotypes, such as inattention, impulsivity, aggressive behavior, and novelty seeking personality trait are presented, because recent studies have applied quantitative trait measures using questionnaires, symptom scales, or other objective endophenotypes. Unfortunately, genetic variants with minor effects are problematic to detect in these complex inheritance disorders, often leading to contradictory results. The most consistent association findings relate to ADHD and the dopamine transporter and the dopamine D4 receptor genes. Meta-analyses also support the association between substance abuse and the D2 receptor gene. The dopamine catabolizing enzyme genes, such as monoamine oxidase (MAO) A and catechol-O-methyltransferase (COMT) genes, have been linked to aggressive behaviors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.