Evidence map›Paper›PMID 21527165›Full record

ArticleJournal of the American Medical Directors Association2011

Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia.

Roger A Fielding, Bruno Vellas, William J Evans, Shalender Bhasin, John E Morley, Anne B Newman, Gabor Abellan van Kan, Sandrine Andrieu, Juergen Bauer, Denis Breuille and 15 more

5 registry-linked trialsAbstract readConsensus Statement
In one paragraph

Article in Journal of the American Medical Directors Association, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 1,565 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,565citing papers in PubMed, 11 pooled it
70.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04140864 completednot on this mapstarted 2018, after this paper: background citation

Prevalence of Sarcopenic Obesity Among Community Dwelling Elderly: A Pilot Study

TypeobservationalSponsorUniversiti Tunku Abdul RahmanRan2018 to 2019Enrolled65ConditionsSarcopenic Obesity
NCT04306562 naterminatednot on this mapstarted 2019, after this paper: background citation

Effect of Oral Protein Supplementation on Postoperative Complications in Elderly Sarcopenic Cancerous Patients: A Randomized Controlled Trial

TypeinterventionalSponsorSiriraj HospitalRan2019 to 2024Enrolled5ConditionsSarcopenia, CancerArmsenteral nutrition supplement
NCT04780126 unknown statusnot on this mapstarted 2021, after this paper: background citation

Measuring the Loss of Skeletal Muscle Mass in the Hospitalized Patient With the Diagnosis of COVID-19

Typeobservational_patient_registrySponsorFundacion para la Investigacion Biomedica del Hospital Universitario la PazRan2021 to 2021Enrolled64ConditionsSarcopenia, Covid19ArmsSarcopenia diagnosis
NCT05875597 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Detection of Clinical-functional Changes Following Exercise Therapy and Education in Institutionalised and Community-dwelling Older Adults Diagnosed With Sarcopenia

TypeinterventionalSponsorUniversity of ExtremaduraRan2023 to 2023Enrolled50ConditionsResistance Training, Aged, Nursing Homes, SarcopeniaArmsPhysical therapy exercise programme
NCT07269600 active not recruitingnot on this mapstarted 2025, after this paper: background citation

The Effects of Sarcopenia on Cervical Proprioception, Kinesiophobia and Pressure Pain Threshold in Geriatric Nursing Home Residents

Typeobservational_patient_registrySponsorAtılım UniversityRan2025 to 2026Enrolled31ConditionsSarcopenia in Elderly
3 · Its place in the literature

Who cites it

1,565 citing papers in PubMed, 11 syntheses or guidelines pooled it, 3,227 citations in OpenAlex.

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1,505 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 20 institutions in 7 countries.

Roger A FieldingNutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Boston, MA 02111, USA. roger.fielding@tufts.edu
Bruno Vellas
William J Evans
Shalender Bhasin
John E Morley
Anne B Newman
Gabor Abellan van Kan
Sandrine Andrieu
Juergen Bauer
Denis Breuille
Tommy Cederholm
Julie Chandler
Capucine De Meynard
Lorenzo Donini
Tamara Harris
Aimo Kannt
Florence Keime Guibert
Graziano Onder
Dimitris Papanicolaou
Yves Rolland
Daniel Rooks
Cornel Sieber
Elisabeth Souhami
Sjors Verlaan
Mauro Zamboni
Hôpital de La Grave · FRInserm · FRMerck & Co., Inc., Rahway, NJ, USA (United States) · USBoston University · USChiesi (France) · FRDanone (Netherlands) · NLFriedrich-Alexander-Universität Erlangen-Nürnberg · DEGlaxoSmithKline (United States) · USJean Mayer Human Nutrition Research Center on Aging · USNational Institute on Aging · USNestlé (Switzerland) · CHNovartis (United States) · USNuremberg Hospital · DESaint Louis University · USSanofi (France) · FRSanofi (Germany) · DESapienza University of Rome · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Pittsburgh · USUniversity of Verona · IT

Funding

UF FIELD CENTERU01AG022376 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PAHOR, MARCO · 2003 to 2015
$83.3M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
LOWER EXTREMITY MUSCLE POWER AND FUNCTION IN THE ELDERLYR01AG018844 · NIA · TUFTS UNIVERSITY BOSTON · PI FIELDING, ROGER A. · 2001 to 2009
$3.0M
Activity-dependent signaling in aging skeletal muscleR03AG025270 · NIA · TUFTS UNIVERSITY BOSTON · PI FIELDING, ROGER A. · 2005 to 2006
$145k
NCATS NIH HHS UL1 TR000005NIA NIH HHS P30 AG028740NIA NIH HHS R01 AG018844NIA NIH HHS R03 AG025270NIA NIH HHS U01 AG022376
6 · The paper itself

Abstract

Sarcopenia, the age-associated loss of skeletal muscle mass and function, has considerable societal consequences for the development of frailty, disability, and health care planning. A group of geriatricians and scientists from academia and industry met in Rome, Italy, on November 18, 2009, to arrive at a consensus definition of sarcopenia. The current consensus definition was approved unanimously by the meeting participants and is as follows: Sarcopenia is defined as the age-associated loss of skeletal muscle mass and function. The causes of sarcopenia are multifactorial and can include disuse, altered endocrine function, chronic diseases, inflammation, insulin resistance, and nutritional deficiencies. Although cachexia may be a component of sarcopenia, the 2 conditions are not the same. The diagnosis of sarcopenia should be considered in all older patients who present with observed declines in physical function, strength, or overall health. Sarcopenia should specifically be considered in patients who are bedridden, cannot independently rise from a chair, or who have a measured gait speed less that 1 m/s(-1). Patients who meet these criteria should further undergo body composition assessment using dual energy x-ray absorptiometry with sarcopenia being defined using currently validated definitions. A diagnosis of sarcopenia is consistent with a gait speed of less than 1 m·s(-1) and an objectively measured low muscle mass (eg, appendicular mass relative to ht(2) that is ≤ 7.23 kg/m(2) in men and ≤ 5.67 kg/m(2) in women). Sarcopenia is a highly prevalent condition in older persons that leads to disability, hospitalization, and death.

Indexed as

Diagnostic ErrorsInternationalitySarcopeniaAgedAged, 80 and overFemaleHumansMaleMiddle Aged

Identifiers

PMID21527165
PMCPMC3377163
OpenAlexW1965927192

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.