ArticleJournal of cultural diversity2011
Willingness to participate in clinical trials among African Americans and whites previously exposed to clinical research.
Article in Journal of cultural diversity, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Recruitment and retention strategies for improving representation in clinical research: A meta-synthesis.PloS one · 2025Pooled it
- Improving African American women's engagement in clinical research: A systematic review of barriers to participation in clinical trials.Journal of the National Medical Association · 2022Pooled it
- Effect of an Early Palliative Care Telehealth Intervention vs Usual Care on Patients With Heart Failure: The ENABLE CHF-PC Randomized Clinical Trial.JAMA internal medicine · 2020Trial
- Engaging patients and families to create a feasible clinical trial integrating palliative and heart failure care: results of the ENABLE CHF-PC pilot clinical trial.BMC palliative care · 2017Trial
- Predictors of willingness to participate in window-of-opportunity breast trials.Clinical medicine & research · 2013Trial
- Clinical trial recruitment of adult African American smokers from economically disadvantaged urban communities.Journal of ethnicity in substance abuseTrial
- Racial Climate on Willingness to Participate in Clinical Research.Journal of racial and ethnic health disparities · 2026Article
- How Many Anxious Kids in Community Mental Health Would Be Eligible for an RCT? And Does It Matter? Insights from a Naturalistic Sample and a Non-Systematic Review.Children (Basel, Switzerland) · 2026Article
- Clinical Trial Discussion and Participation in a Breast Cancer Cohort by Race and Ethnicity.JAMA network open · 2025Article
- Promoting Diversity through an Understanding of Barriers and Drivers for Inclusive Clinical Trials.Therapeutic innovation & regulatory science · 2025Article
- Factors Associated With Minority Patient Enrollment in a Gastric Cancer Biobank.The Journal of surgical research · 2025Article
- Development and validation of Join Clinical Trial Questionnaire (JoinCT).Asia-Pacific journal of clinical oncology · 2025Article
- Theory of planned behavior constructs are associated with willingness to engage in clinical trial interventions for chronic low back pain: A cross-sectional survey study.Journal of clinical and translational science · 2025Article
- Clinical Trial Diversity, Equity, and Inclusion: Roadmap of the Cardiothoracic Surgical Trials Network.The Annals of thoracic surgery · 2024Review
- Correlates of health-related quality of life in African Americans diagnosed with cancer: a review of survivorship studies and the Detroit research on cancer survivors cohort.Cancer metastasis reviews · 2024Review
- Perceptions about dementia clinical trials among underrepresented populations: a nationally representative survey of U.S. dementia caregivers.Alzheimer's research & therapy · 2024Article
- Teaching gender medicine can enhance the quality of healthcare.American heart journal plus : cardiology research and practice · 2024Article
- More than Just a Number: Perspectives from Black Male Participants on Community-Based Interventions and Clinical Trials to Address Cardiovascular Health Disparities.International journal of environmental research and public health · 2024Article
- Access to and interest in human milk research opportunities among Black pregnant and postpartum people.Frontiers in nutrition · 2024Article
- A Conceptual Model to Achieve Health Equity in APOL-1 Clinical Studies.Health equity · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The objective of this study was to identify racial differences in willingness to participate in a population with previous exposure to clinical research. A survey instrument was administered to community-dwelling whites and African Americans who were voluntarily receiving a lay research and health education newsletter from a local Boston geriatric clinical research institution. The survey instrument assessed willingness to participate in 3 hypothetical clinical trials (diet trial for obesity, medication trial for hypertension [HTN], chemotherapy trial for cancer). Surveys were received from 473 whites and 279 African Americans (53% response rate) with mean age 74 (SD +/- 9). In multivariate models, race was not significantly related to willingness to participate in the multivariate models for any of the 3 trials. Previous trial participation was related to a higher odds of willingness to participate in the diet trial only (OR 1.8, 95% CI 1.2, 2.6). Lower levels of trust in one's primary care physician were associated with a lower odds of willingness to participate in clinical trials for the diet and HTN trials (OR 0.5, 95% CI 0.3, 0.8 and OR 0.6, 95% CI 0.3, 0.9, respectively). These findings suggest that, within populations previously exposed to clinical research, African Americans are no less willing to participate in clinical trials compared to whites.
Indexed as
Identifiers
21526582PMC3241443What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.