Evidence map›Paper›PMID 21526421›Full record

ArticleHeart and vessels2012

Impact of obesity on plasma B-type natriuretic peptide levels in Japanese community-based subjects.

Megumi Koizumi, Hiroyuki Watanabe, Yoshihiro Kaneko, Kenji Iino, Masaru Ishida, Toshimitsu Kosaka, Yutaka Motohashi, Hiroshi Ito

Abstract read
PubMed Publisher
In one paragraph

Article in Heart and vessels, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Diabetes Mellitus and Heart Failure.European cardiology · 2014
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Megumi KoizumiDivision of Cardiovascular Medicine, Department of Internal Medicine, Akita University Faculty of Medicine, 1-1-1 Hondo, Akita City, Akita, 010-8543, Japan.
Hiroyuki Watanabe
Yoshihiro Kaneko
Kenji Iino
Masaru Ishida
Toshimitsu Kosaka
Yutaka Motohashi
Hiroshi Ito
Akita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The plasma B-type natriuretic peptide (BNP) concentration was recently shown to be inversely correlated with body mass index (BMI). However, very few attempts have been made to associate abdominal obesity and BNP in the Japanese general population. Here, we conducted a cross-sectional study, and examined 339 male and 429 female residents without heart disease in a rural Japanese community who received an annual health checkup in 2006. BNP was inversely associated with both BMI and abdominal circumference (AC) in the age-adjusted regression analysis (p < 0.05). Following adjustment for traditional risk factors, multiple regression analysis revealed that BNP was negatively correlated with AC (p < 0.05), but not BMI. Although metabolic syndrome was not associated with BNP levels, AC had an influence on low BNP levels in the multiple regression analysis using both AC and BMI concurrently (p < 0.05 for AC and p > 0.60 for BMI). These effects were more prominent in men than in women. Collectively, plasma BNP levels are inversely related with obesity, as measured by AC, in Japanese community-based subjects.

Indexed as

AdultAgedAged, 80 and overAsian PeopleBiomarkersBody Mass IndexCardiovascular DiseasesCross-Sectional StudiesFemaleHumansJapanMaleMiddle AgedNatriuretic Peptide, BrainObesity, AbdominalRegression AnalysisBiomarkersNatriuretic Peptide, Brain

Identifiers

PMID21526421
OpenAlexW1991413489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.