Evidence map›Paper›PMID 21525820›Full record

ReviewMedical science monitor : international medical journal of experimental and clinical research2011

Candidemia in children after complex congenital heart defects surgery treated with caspofungin--our own experience and a review of literature.

Radoslaw Jaworski, Ninela Irga, Ireneusz Haponiuk, Maciej Chojnicki, Elzbieta Arlukowicz, Mariusz Steffek, Mariusz Sroka, Katarzyna Gierat-Haponiuk, Jacek Juscinski, Lucyna Palkowska and 2 more

Open access · hybridAbstract readCase ReportsReview
In one paragraph

Review in Medical science monitor : international medical journal of experimental and clinical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Novel GATA4 mutations in patients with congenital ventricular septal defects.Medical science monitor : international medical journal of experimental and clinical research · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Radoslaw JaworskiDepartment of Pediatric Cardiac Surgery, Mikołaj Kopernik Pomeranian Centre of Traumatology, Gdansk, Poland. radicis@go2.pl
Ninela Irga
Ireneusz Haponiuk
Maciej Chojnicki
Elzbieta Arlukowicz
Mariusz Steffek
Mariusz Sroka
Katarzyna Gierat-Haponiuk
Jacek Juscinski
Lucyna Palkowska
Aneta Sendrowska
Wojciech Kosiak
Gdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInvasive fungal infections due to Candida species constitute an increasing clinical problem. There are no guidelines for the management of candidemia in children undergoing surgical procedures for congenital heart defects (CHD). The aim of the study was to draw attention to the problem of candidemia in children who are operated on due to congenital heart defects. MATERIAL/

methodsWe retrospectively analyzed medical documentation of 307 children with congenital heart defects treated in 1 clinical centre in Poland, from whom we selected those diagnosed with candidemia during the postoperative period. Next, we analyzed in detail the clinical course of invasive candidiasis in each individual and we performed an analysis of risk factors that lead to candidemia.

resultsIn the analyzed period, among 307 children who underwent surgical procedures, we observed 2 cases of candidemia (0.65%) which were effectively cured with caspofungin. No adverse effects were observed after treatment with the drug.

conclusionsCandidemia in children who undergo surgical treatment of congenital heart defects is an important factor that can influence final clinical results. Caspofungin may be an effective therapeutic option when treating candidemia in children after extensive cardiosurgical procedures.

Indexed as

Antifungal AgentsCandidemiaCardiac Surgical ProceduresCaspofunginChildC-Reactive ProteinEchinocandinsFemaleHeart Defects, CongenitalHumansInfantLeukocyte CountLipopeptidesAntifungal AgentsCaspofunginC-Reactive ProteinEchinocandinsLipopeptides

Identifiers

PMID21525820
PMCPMC3539598
OpenAlexW2051835947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.