Evidence map›Paper›PMID 21525646›Full record

ArticleJournal of synchrotron radiation2011

Experimental procedure for the characterization of radiation damage in macromolecular crystals.

Ricardo M F Leal, Gleb P Bourenkov, Olof Svensson, Darren Spruce, Matias Guijarro, Alexander N Popov

Open access · hybridAbstract read
In one paragraph

Article in Journal of synchrotron radiation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Towards routine accurate electron-density studies of biological macromolecules.Acta crystallographica. Section D, Structural biology · 2026
    Article
  2. Article
  3. Article
  4. Automated workflows for strategy computation and data collection at synchrotron beamlines.Acta crystallographica. Section D, Structural biology · 2026
    Article
  5. Article
  6. Article
  7. How best to use photons.Acta crystallographica. Section D, Structural biology · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Data collection for crystallographic structure determination.Methods in molecular biology (Clifton, N.J.) · 2014
    Article
  14. Predicting the X-ray lifetime of protein crystals.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  15. Squeezing the most from every crystal: the fine details of data collection.Acta crystallographica. Section D, Biological crystallography · 2013
    Article
  16. Article
  17. Article
  18. Measurement of the equilibrium relative humidity for common precipitant concentrations: facilitating controlled dehydration experiments.Acta crystallographica. Section F, Structural biology and crystallization communications · 2012
    Article
  19. A multi-dataset data-collection strategy produces better diffraction data.Acta crystallographica. Section A, Foundations of crystallography · 2011
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ricardo M F LealESRF, Rue Jules Horowitz, BP 220, Grenoble, France.
Gleb P Bourenkov
Olof Svensson
Darren Spruce
Matias Guijarro
Alexander N Popov
European Science Foundation · FREuropean Molecular Biology Laboratory · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A reliable and reproducible method to automatically characterize the radiation sensitivity of macromolecular crystals at the ESRF beamlines has been developed. This new approach uses the slope of the linear dependence of the overall isotropic B-factor with absorbed dose as the damage metric. The method has been implemented through an automated procedure using the EDNA on-line data analysis framework and the MxCuBE data collection control interface. The outcome of the procedure can be directly used to design an optimal data collection strategy. The results of tests carried out on a number of model and real-life crystal systems are presented.

Identifiers

PMID21525646
PMCPMC3268693
OpenAlexW2091133300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.