ArticleJournal of neurophysiology2011
Chemosensory burst coding by mouse vomeronasal sensory neurons.
Article in Journal of neurophysiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Combinatorial responsiveness of chemosensory neurons in mouse explants revealed by DynamicNeuroTracker.Cell reports methods · 2025Article
- CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Bruce effect: Representational stability and memory formation in the accessory olfactory bulb of the female mouse.Cell reports · 2022Article
- Synchronous Infra-Slow Oscillations Organize Ensembles of Accessory Olfactory Bulb Projection Neurons into Distinct Microcircuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Odor tracking in aquatic organisms: the importance of temporal and spatial intermittency of the turbulent plume.Scientific reports · 2020Article
- Initial Characterization of a Subpopulation of Inherent Oscillatory Mammalian Olfactory Receptor Neurons.Chemical senses · 2019Article
- Signal Detection and Coding in the Accessory Olfactory System.Chemical senses · 2018Review
- Temporal Response Properties of Accessory Olfactory Bulb Neurons: Limitations and Opportunities for Decoding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Faecal bile acids are natural ligands of the mouse accessory olfactory system.Nature communications · 2016Article
- Neurally Encoding Time for Olfactory Navigation.PLoS computational biology · 2016Article
- Functional organization of glomerular maps in the mouse accessory olfactory bulb.Nature neuroscience · 2014Article
- Intermittency coding in the primary olfactory system: a neural substrate for olfactory scene analysis.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Mechanisms underlying odorant-induced and spontaneous calcium signals in olfactory receptor neurons of spiny lobsters, Panulirus argus.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014Article
- Reliable sex and strain discrimination in the mouse vomeronasal organ and accessory olfactory bulb.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Spontaneous and sensory-evoked activity in mouse olfactory sensory neurons with defined odorant receptors.Journal of neurophysiology · 2013Article
- Organization of vomeronasal sensory coding revealed by fast volumetric calcium imaging.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
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2 authors.
Funding
Abstract
The capabilities of any sensory system are ultimately constrained by the properties of the sensory neurons: the ability to detect and represent stimuli is limited by noise due to spontaneous activity, and optimal decoding in downstream circuitry must be matched to the nature of the encoding performed at the input. Here, we investigated the firing properties of sensory neurons in the accessory olfactory system, a distinct sensory system specialized for detection of socially relevant odors. Using multielectrode array recording, we observed that sensory neurons are spontaneously active and highly variable across time and trials and that this spontaneous activity limits the ability to distinguish sensory responses from noise. Sensory neuron activity tended to consist of bursts that maintained remarkably consistent statistics during both spontaneous activity and in response to stimulation with sulfated steroids. This, combined with pharmacological and genetic intervention in the signal transduction cascade, indicates that sensory transduction plays a role in shaping overall spontaneous activity. These findings indicate that as-yet unexplored characteristics of the sensory transduction cascade significantly constrain the representation of sensory information by vomeronasal neurons.
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