Evidence map›Paper›PMID 21525224›Full record

ArticleJournal of clinical microbiology2011

Impact of rpoB mutations on reduced vancomycin susceptibility in Staphylococcus aureus.

Yukiko Watanabe, Longzhu Cui, Yuki Katayama, Kishii Kozue, Keiichi Hiramatsu

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Review
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  3. Host-driven remodelling of theMicrobiology (Reading, England) · 2026
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  10. Teicoplanin associated geneFrontiers in microbiology · 2023
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  11. Article
  12. Molecular Basis of Non-β-Lactam Antibiotics Resistance inAntibiotics (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Article
  15. Genetic Mechanisms of Vancomycin Resistance inAntibiotics (Basel, Switzerland) · 2022
    Review
  16. Recombineering in Staphylococcus aureus.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  17. Molecular Characterization of Rifampicin-ResistantAntibiotics (Basel, Switzerland) · 2021
    Article
  18. Article
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yukiko WatanabeDepartment of Bacteriology, Graduate School of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Longzhu Cui
Yuki Katayama
Kishii Kozue
Keiichi Hiramatsu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Of 38 vancomycin-intermediate Staphylococcus aureus (VISA) clinical strains, 27 (71%) possessed a mutation(s) in rpoB encoding the β-subunit of RNA polymerase. Furthermore, 95.6% of the rifampin-resistant mutants obtained from 9 methicillin-resistant S. aureus (MRSA) clinical isolates showed decreased vancomycin susceptibilities. These data indicate the involvement of an rpoB mutation in VISA phenotype expression.

Indexed as

Mutation, MissenseVancomycin ResistanceDNA-Directed RNA PolymerasesHumansMicrobial Sensitivity TestsStaphylococcal InfectionsStaphylococcus aureusVancomycinDNA-Directed RNA PolymerasesRNA polymerase beta subunitVancomycin

Identifiers

PMID21525224
PMCPMC3147882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.