Evidence map›Paper›PMID 21525221›Full record

ArticleJournal of clinical microbiology2011

Clinical and molecular observations of two fatal cases of rotavirus-associated enteritis in children in Italy.

Maria Cristina Medici, Laura Anna Abelli, Monica Martinelli, Domenico Corradi, Icilio Dodi, Fabio Tummolo, Valeria Albonetti, Vito Martella, Giuseppe Dettori, Carlo Chezzi

Abstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Frontiers in cellular and infection microbiology · 2022
    Article
  3. Article
  4. Rotavirus NSP4Virus genes · 2017
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Maria Cristina MediciSection of Microbiology, Unit of Paediatrics and Oncohematology, Maternal-Infantile Department, University Hospital of Parma, Viale A Gramsci 14, 43126 Parma, Italy. mariacristina.medici@unipr.it
Laura Anna Abelli
Monica Martinelli
Domenico Corradi
Icilio Dodi
Fabio Tummolo
Valeria Albonetti
Vito Martella
Giuseppe Dettori
Carlo Chezzi
University of Parma · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two fatal cases of infantile rotavirus enteritis occurred in northern Italy in 2005. Both children were severely dehydrated, and death was related to severe cerebral edema. Histological examination demonstrated extensive damage of the intestinal epithelium, villous atrophy or blunting, and macrophage infiltration. The two rotavirus strains were of the G1P[8] type and the long electropherotype. The 2005 G1P[8] rotaviruses differed in the NSP4, VP3, VP4, and VP7 genes from G1P[8] rotaviruses circulating in 2004, suggesting the onset of a new G1P[8] strain in the local population.

Indexed as

Brain EdemaChild, PreschoolCluster AnalysisEnteritisFatal OutcomeGenotypeHistocytochemistryHumansInfantIntestinal MucosaItalyMacrophagesMaleMolecular Sequence DataPhylogenyRNA, ViralRNA, ViralViral Proteins

Identifiers

PMID21525221
PMCPMC3147829
OpenAlexW2154791813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.