ArticleEnvironmental health perspectives2011
Case report: high prenatal bisphenol a exposure and infant neonatal neurobehavior.
Article in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00129324 (Neurobehavioral Effects of Prevalent Neurotoxicants in Children), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neurobehavioral Effects of Prevalent Neurotoxicants in Children: A Cohort Study of the Cincinnati Center for Children's Environmental Health
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Bisphenol A exposure and children's behavior: A systematic review.Journal of exposure science & environmental epidemiology · 2017Pooled it
- Unexpected results in a randomized dietary trial to reduce phthalate and bisphenol A exposures.Journal of exposure science & environmental epidemiology · 2013Trial
- Health effects of microplastics and nanoplastics: review of published case reports.Environmental analysis, health and toxicology · 2024Article
- Addressing systemic problems with exposure assessments to protect the public's health.Environmental health : a global access science source · 2023Review
- Therapeutic potential of vitamin D against bisphenol A-induced spleen injury in Swiss albino mice.PloS one · 2023Article
- Food Additives and Child Health.Pediatrics · 2018Article
- Food Additives and Child Health.Pediatrics · 2018Review
- Disruption of neonatal cardiomyocyte physiology following exposure to bisphenol-a.Scientific reports · 2018Article
- Gestational exposure to endocrine disrupting chemicals in relation to infant birth weight: a Bayesian analysis of the HOME Study.Environmental health : a global access science source · 2017Article
- Early life bisphenol A exposure and neurobehavior at 8years of age: Identifying windows of heightened vulnerability.Environment international · 2017Article
- Endocrine Disruption of Vasopressin Systems and Related Behaviors.Frontiers in endocrinology · 2017Review
- Patterns, Variability, and Predictors of Urinary Bisphenol A Concentrations during Childhood.Environmental science & technology · 2016Article
- Physiological response of cardiac tissue to bisphenol A: alterations in ventricular pressure and contractility.American journal of physiology. Heart and circulatory physiology · 2015Article
- Gestational urinary bisphenol A and maternal and newborn thyroid hormone concentrations: the HOME Study.Environmental research · 2015Article
- The adverse cardiac effects of Di(2-ethylhexyl)phthalate and Bisphenol A.Cardiovascular toxicology · 2014Review
- Early-life bisphenol a exposure and child body mass index: a prospective cohort study.Environmental health perspectives · 2014Article
- Article
- A round robin approach to the analysis of bisphenol A (BPA) in human blood samples.Environmental health : a global access science source · 2014Article
- Sex specific impact of perinatal bisphenol A (BPA) exposure over a range of orally administered doses on rat hypothalamic sexual differentiation.Neurotoxicology · 2013Article
- Bisphenol a exposure disrupts genomic imprinting in the mouse.PLoS genetics · 2013Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
contextMost of the U.S. population is exposed to the high-production-volume chemical bisphenol A (BPA), but targetable sources of exposure remain to be determined. Animal studies and one human study suggest that BPA is a neurotoxicant. CASE PRESENTATION: A mother in the Health Outcomes and Measures of the Environment (HOME) Study, a prospective birth cohort examining prenatal and postnatal environmental toxicants and childhood health outcomes, had a urinary BPA concentration of 583 µg/g creatinine at 27 weeks of pregnancy, which was the highest concentration observed in this cohort (median, 2.0 µg/g creatinine) and the general population. We used prenatal questionnaire data and a follow-up interview to identify potential sources of exposure that included daily plastic use and consumption of canned beverages and foods. Her male infant had a normal newborn neurobehavioral assessment but presented with abnormalities at the 1-month examination that prompted physician referral. Subsequently, the child had normal neurobehavioral testing results at annual evaluations from 1 to 5 years of age. DISCUSSION: Investigations into sources of high gestational urinary BPA concentrations provide an opportunity to identify potential targets for reduction of BPA exposure. This case highlights a potential link between gestational BPA exposure and transient neurobehavioral changes that is hypothesis generating and can serve to alert researchers to potential areas for examination in future studies. RELEVANCE TO CLINICAL PRACTICE: It is important to educate health care practitioners regarding potential sources of BPA exposure and anticipatory guidance on minimization of exposures during vulnerable periods of development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.