ArticleBiosensors & bioelectronics2011
Silicon photonic crystal nanocavity-coupled waveguides for error-corrected optical biosensing.
Article in Biosensors & bioelectronics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Dispersion Engineering and Sensitivity Enhancement in Photonic Crystal Waveguide Sensors: Current Advances and Emerging Challenges.Sensors (Basel, Switzerland) · 2026Review
- Inverse design of compact silicon photonic waveguide reflectors and their application for Fabry-Perot resonators.Nanophotonics (Berlin, Germany) · 2024Article
- Advancements and Perspectives in Optical Biosensors.ACS omega · 2024Review
- Gradient Guided-Mode Resonance Biosensor with Smartphone Readout.Biosensors · 2023Article
- Balancing detectivity and sensitivity of plasmonic sensors with surface lattice resonance.Nanophotonics (Berlin, Germany) · 2023Article
- Progress of infrared guided-wave nanophotonic sensors and devices.Nano convergence · 2020Review
- Towards Portable Nanophotonic Sensors.Sensors (Basel, Switzerland) · 2019Review
- Silicon Photonic Biosensors Using Label-Free Detection.Sensors (Basel, Switzerland) · 2018Review
- Optical Micro/Nanofiber-Based Localized Surface Plasmon Resonance Biosensors: Fiber Diameter Dependence.Sensors (Basel, Switzerland) · 2018Article
- Article
- Degradation of silicon photonic biosensors in cell culture media: analysis and prevention.Biomedical optics express · 2017Article
- Recognition-mediated particle detection under microfluidic flow with waveguide-coupled 2D photonic crystals: towards integrated photonic virus detectors.Lab on a chip · 2017Article
- Last Advances in Silicon-Based Optical Biosensors.Sensors (Basel, Switzerland) · 2016Review
- Direct detection of transcription factors in cotyledons during seedling development using sensitive silicon-substrate photonic crystal protein arrays.Plant physiology · 2015Article
- Two-dimensional photonic crystals for sensitive microscale chemical and biochemical sensing.Lab on a chip · 2015Review
- Examining the interactions of the splicing factor MBNL1 with target RNA sequences via a label-free, multiplex method.Analytical chemistry · 2014Article
- Enhancing the detection limit of nanoscale biosensors via topographically selective functionalization.Analytical chemistry · 2014Article
- Selective virus detection in complex sample matrices with photonic crystal optical cavities.Biosensors & bioelectronics · 2013Article
- Photonic crystal sensors based on porous silicon.Sensors (Basel, Switzerland) · 2013Article
- Detection of Myoglobin with an Open-Cavity-Based Label-Free Photonic Crystal Biosensor.Journal of medical engineering · 2013Article
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Authors and funding
5 authors.
Funding
Abstract
A photonic crystal (PhC) waveguide based optical biosensor capable of label-free and error-corrected sensing was investigated in this study. The detection principle of the biosensor involved shifts in the resonant mode wavelength of nanocavities coupled to the silicon PhC waveguide due to changes in ambient refractive index. The optical characteristics of the nanocavity structure were predicted by FDTD theoretical methods. The device was fabricated using standard nanolithography and reactive-ion-etching techniques. Experimental results showed that the structure had a refractive index sensitivity of 10(-2) RIU. The biosensing capability of the nanocavity sensor was tested by detecting human IgG molecules. The device sensitivity was found to be 2.3±0.24×10(5) nm/M with an achievable lowest detection limit of 1.5 fg for human IgG molecules. Additionally, experimental results demonstrated that the PhC devices were specific in IgG detection and provided concentration-dependent responses consistent with Langmuir behavior. The PhC devices manifest outstanding potential as microscale label-free error-correcting sensors, and may have future utility as ultrasensitive multiplex devices.
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