ReviewNature reviews. Gastroenterology & hepatology2011
Treatment and surveillance strategies in achalasia: an update.
Review in Nature reviews. Gastroenterology & hepatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 61 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Peroral Endoscopic Remyotomy for Failed Heller Myotomy
Clinical Impact of Peroral Endoscopic Myotomy for Esophageal Achalasia
Who cites it
61 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Is peroral endoscopic myotomy (POEM) more effective than pneumatic dilation and Heller myotomy? A systematic review and meta-analysis.Surgical endoscopy · 2021Pooled it
- Anterior Dor or Posterior Toupet with Heller Myotomy for Achalasia Cardia: A Systematic Review and Meta-Analysis.World journal of surgery · 2019Pooled it
- Aflatoxin influences achalasia symptomatology.Molecular medicine reports · 2020Trial
- Peroral endoscopic myotomy for advanced achalasia with sigmoid-shaped esophagus: long-term outcomes from a prospective, single-center study.Surgical endoscopy · 2015Trial
- Major Basic Protein Deposition Without Eosinophilic Infiltration in Hypercontractile Esophagus: A Case Report.DEN open · 2026Article
- Peroral endoscopic myotomy provides effective and sustained relief for achalasia in Allgrove syndrome: a long-term comparative cohort study.Frontiers in medicine · 2026Article
- Peroral endoscopic myotomy in spastic esophageal disorders: Clinical outcomes and optimal approaches.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025Article
- Endoscopic ultrasound navigated application of botulinum toxin in severe esophageal motility disorder.Clinical journal of gastroenterology · 2025Article
- Comparison of peroral endoscopic myotomy, laparoscopic Heller myotomy, and pneumatic dilation for patients with achalasia: a United States national experience.Clinical endoscopy · 2025Article
- Pre- and post-intervention oesophageal pressure topography metrics in the three subtypes of achalasia: A pilot study on Indian adults.Medical journal, Armed Forces India · 2024Article
- Comparison of laparoscopic Heller myotomy and endoscopic balloon dilation in the treatment of achalasia: Effects on quality of life and patient satisfaction.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024Article
- Timed barium esophagography to predict recurrent achalasia after peroral endoscopic myotomy: a retrospective study in Thailand.Clinical endoscopy · 2024Article
- Impedance planimetry during per-oral endoscopic myotomy is associated with decreased inadvertent capnoperitoneum.Surgical endoscopy · 2024Article
- Incidence, Morbidity, and Mortality of Achalasia: A Nationwide, Population-Based Cohort Study in South Korea.Gut and liver · 2023Article
- What role does the submucosa play in the pathophysiology and treatment of achalasia? An analysis of impedance planimetry during POEM.Surgical endoscopy · 2023Article
- Repeat peroral endoscopic myotomy with simultaneous submucosal and muscle dissection as a salvage option for recurrent achalasia.World journal of gastroenterology · 2023Article
- Per-oral endoscopic myotomy for the treatment of non-achalasia esophageal dysmotility disorders: experience from a single high-volume center.Surgical endoscopy · 2023Article
- Per-oral endoscopic dual myotomy for the treatment of achalasia.Esophagus : official journal of the Japan Esophageal Society · 2021Article
- Does laparoscopic reoperation yield symptomatic improvements similar to those of primary laparoscopic Heller myotomy in achalasia patients?Surgical endoscopy · 2021Article
- Peroral endoscopic myotomy for the treatment of esophageal diverticulum: an experience in China.Surgical endoscopy · 2021Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Controversy exists with regard to the optimal treatment for achalasia and whether surveillance for early recognition of late complications is indicated. Currently, surgical myotomy and pneumatic dilation are the most effective treatments for patients with idiopathic achalasia, and a multicenter, randomized, international trial has confirmed similar efficacy of these treatments, at least in the short term. Clinical predictors of outcome, patient preferences and local expertise should be considered when making a decision on the most appropriate treatment option. Owing to a lack of long-term benefit, endoscopic botulinum toxin injection and medical therapies are reserved for patients of advanced age and those with clinically significant comorbidites. The value of new endoscopic, radiologic or surgical treatments, such as peroral endoscopic myotomy, esophageal stenting and robotic-assisted myotomy has not been fully established. Finally, long-term follow-up data in patients with achalasia support the notion that surveillance strategies might be beneficial after a disease duration of more than 10-15 years.
Indexed as
Identifiers
21522116What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.