ArticleJournal of acquired immune deficiency syndromes (1999)2011
A twin response to twin epidemics: integrated HIV/syphilis testing at STI clinics in South China.
Article in Journal of acquired immune deficiency syndromes (1999), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- The cost-effectiveness of syphilis screening in pregnant women: a systematic literature review.Frontiers in public health · 2024Pooled it
- Missed opportunities for HIV testing among those who accessed sexually transmitted infection (STI) services, tested for STIs and diagnosed with STIs: a systematic review and meta-analysis.Journal of the International AIDS Society · 2023Pooled it
- Risk Factors of HIV and Other Sexually Transmitted Infections in China: A Systematic Review of Reviews.PloS one · 2015Pooled it
- Pay-it-forward gonorrhoea and chlamydia testing among men who have sex with men in China: a randomised controlled trial.The Lancet. Infectious diseases · 2020Trial
- Experiences of Integration of HIV, Hepatitis, and Sexually Transmitted Infection Services Across Different Countries Worldwide: A Scoping Review.Health science reports · 2026Article
- Integration of HIV, Hepatitis B, and C, and sexually transmitted infections services: A scoping review of the benefits and challenges.PloS one · 2026Article
- A Digital Health Intervention on Healthy Behaviors Among Men Who Have Sex with Men in China Based on Information-Motivation-Behavioral Skills Model: An Exploratory Real-World Study.International journal of sexual health : official journal of the World Association for Sexual Health · 2025Article
- Do the same socio-demographic variables predict testing uptake and sero-status? HIV and syphilis among an observational sample of Chinese men who have sex with men in Shanghai, China.International journal of STD & AIDS · 2020Observational
- Pay-it-forward gonorrhea and chlamydia testing among men who have sex with men in China: a study protocol for a three-arm cluster randomized controlled trial.Infectious diseases of poverty · 2019Article
- Low Chlamydia and Gonorrhea Testing Rates Among Men Who Have Sex With Men in Guangdong and Shandong Provinces, China.Sexually transmitted diseases · 2019Article
- Pay-it-forward strategy to enhance uptake of dual gonorrhea and chlamydia testing among men who have sex with men in China: a pragmatic, quasi-experimental study.The Lancet. Infectious diseases · 2019Article
- Expanding syphilis testing: a scoping review of syphilis testing interventions among key populations.Expert review of anti-infective therapy · 2018Article
- The Distribution of Syphilis Among Inpatients in Wenzhou, China: A Hospital Based Study.Jundishapur journal of microbiology · 2016Article
- Poor Reporting of Outcomes Beyond Accuracy in Point-of-Care Tests for Syphilis: A Call for a Framework.AIDS research and treatment · 2014Review
- HIV and hepatitis C virus test uptake at methadone clinics in Southern China: opportunities for expanding detection of bloodborne infections.BMC public health · 2013Article
- Factors associated with psychosocial services in ogun state, Nigeria.Journal of family medicine and primary care · 2013Article
- Social determinants of syphilis in South China: the effect of sibling position on syphilis and sexual risk behaviours.BMJ open · 2013Article
- Point-of-care testing for sexually transmitted infections: recent advances and implications for disease control.Current opinion in infectious diseases · 2013Review
- HIV and hepatitis C virus testing delays at methadone clinics in Guangdong Province, China.PloS one · 2013Article
- The effect of a structural intervention for syphilis control among 3597 female sex workers: a demonstration study in South China.The Journal of infectious diseases · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundHIV testing is still stigmatized among many high-risk groups in China, whereas routine syphilis testing has been widely accepted at sexually transmitted infection (STI) clinics. This project used the platform of a rapid syphilis screening test to expand HIV test uptake. The objective of this study was to use multilevel modeling to analyze determinants of syphilis and HIV-testing uptake at STI clinics in China.
methods2061 STI patients at 6 clinics in Guangdong Province were offered free rapid syphilis and free rapid HIV testing. Test uptake was defined by patient receipt of results and a multilevel model was used to analyze predictors of uptake.
resultsThis was the first syphilis or HIV test for the large majority (1388, 77.7%) of participants. Syphilis test uptake and HIV test uptake were high (1681, 81.6%, syphilis test uptake; 1673, 81.2% HIV test uptake). HIV test uptake was significantly concordant with syphilis test uptake (τb = 0.89, P < 0.001). The most parsimonious model of refusing HIV test uptake included the following variables: being married, having a previous HIV test, being unaccompanied, and participating in the last 2 months of the study.
conclusionsSTI clinic-based screening for syphilis and HIV represents an excellent opportunity for scaling up integrated services, especially in South China where syphilis and sexually transmitted HIV cases are both rapidly increasing. Effective integration of HIV testing into routine clinical practice requires an understanding not only of individual test uptake but also of the broader social context of HIV testing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.