Evidence map›Paper›PMID 21521419›Full record

ReviewOral diseases2011

Point-of-care oral-based diagnostics.

R W Hart, M G Mauk, C Liu, X Qiu, J A Thompson, D Chen, D Malamud, W R Abrams, H H Bau

Abstract readReview
In one paragraph

Review in Oral diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Great expectorations: the potential of salivary 'omic' approaches in neonatal intensive care.Journal of perinatology : official journal of the California Perinatal Association · 2014
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

R W HartDepartment of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, PA 19104-6315, USA.
M G Mauk
C Liu
X Qiu
J A Thompson
D Chen
D Malamud
W R Abrams
H H Bau

Funding

Point Detection of Pathogens in Oral Samples via UPTU01DE017855 · NIDCR · NEW YORK UNIVERSITY · PI MALAMUD, DANIEL · 2006 to 2010
$7.9M
Point Detection of Pathogens in Oral Samples via UPTU01DE014964 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI MALAMUD, DANIEL · 2002 to 2005
$4.0M
NIDCR NIH HHS U01 DE014964NIDCR NIH HHS U01 DE017855NIDCR NIH HHS U01DE017855
6 · The paper itself

Abstract

Many of the target molecules that reside in blood are also present in oral fluids, albeit at lower concentrations. Oral fluids are, however, relatively easy and safe to collect without the need for specialized equipment and training. Thus, oral fluids provide convenient samples for medical diagnostics. Recent advances in lab-on-a-chip technologies have made minute, fully integrated diagnostic systems practical for an assortment of point-of-care tests. Such systems can perform either immunoassays or molecular diagnostics outside centralized laboratories within time periods ranging from minutes to an hour. The article briefly reviews recent advances in devices for point-of-care testing with a focus on work that has been carried out by the authors as part of a NIH program.

Indexed as

Lab-On-A-Chip DevicesPoint-of-Care SystemsDiagnosis, OralEquipment DesignGingival Crevicular FluidHumansImmunoassayMicrofluidicsMolecular Diagnostic TechniquesSalivaTime Factors

Identifiers

PMID21521419
PMCPMC4273652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.