ArticleClinical endocrinology2011
UK guidance on the initial evaluation of an infant or an adolescent with a suspected disorder of sex development.
Article in Clinical endocrinology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Clinical practice guidelines for the management of differences of sex development in Japan.Endocrine journal · 2026Guideline
- ESPR Uroradiology Taskforce--imaging recommendations in paediatric uroradiology, part VIII: retrograde urethrography, imaging disorder of sexual development and imaging childhood testicular torsion.Pediatric radiology · 2015Guideline
- Guideline
- Androgen insensitivity syndrome: A case report.Medicine · 2026Article
- Case Report: Clinical and molecular genetic analysis of a patient with coexisting complete androgen insensitivity syndrome and neurofibromatosis type 1 and 15pstk + polymorphism.Frontiers in pediatrics · 2026Article
- Clinical practice guidelines for the management of differences of sex development in Japan.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026Review
- Patient and Parent Perceptions of Disorders of Sex Development Terminology: A Pilot Study.Archives of sexual behavior · 2025Article
- The diagnostic value of stimulated androgen ratios in 5-alpha reductase type 2 (SRD5A2) deficiency: a case series and review of the literature.Journal of pediatric endocrinology & metabolism : JPEM · 2025Review
- Excision versus division of Müllerian duct remnants in male disorders of sexual development and differentiation: a prospective study to generate anatomical assessment criteria.Pediatric surgery international · 2025Article
- IUGR ambiguous genitalia in Iran: a case report.Journal of medical case reports · 2025Article
- Swyer Syndrome: A diagnostic challenge.JBRA assisted reproduction · 2025Article
- LGBTQ+ Youth Health: An Unmet Need in Pediatrics.Children (Basel, Switzerland) · 2022Review
- 46,XX DSD: Developmental, Clinical and Genetic Aspects.Diagnostics (Basel, Switzerland) · 2021Review
- Accuracy of Urinary Etiocholanolone/Androsterone Ratio as Alternative to Serum Testosterone/Dihydrotestosterone Ratio for Diagnosis of 5 Alpha-reductase Type 2 Deficiency Patients and Carriers in Indonesia.International journal of endocrinology and metabolism · 2021Article
- Hormone References for Ultrasound Breast Staging and Endocrine Profiling to Detect Female Onset of Puberty.The Journal of clinical endocrinology and metabolism · 2020Article
- Androgens by immunoassay and mass spectrometry in children with 46,XY disorder of sex development.Endocrine connections · 2020Article
- Serum Anti-Müllerian Hormone in the Prediction of Response to hCG Stimulation in Children With DSD.The Journal of clinical endocrinology and metabolism · 2020Article
- Disorders of Sexual Development: Current Status and Progress in the Diagnostic Approach.Current urology · 2020Review
- Next generation sequencing (NGS) to improve the diagnosis and management of patients with disorders of sex development (DSD).Endocrine connections · 2019Article
- Regulation of masculinization: androgen signalling for external genitalia development.Nature reviews. Urology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
It is paramount that any child or adolescent with a suspected disorder of sex development (DSD) is assessed by an experienced clinician with adequate knowledge about the range of conditions associated with DSD. If there is any doubt, the case should be discussed with the regional team. In most cases, particularly in the case of the newborn, the paediatric endocrinologist within the regional DSD team acts as the first point of contact. The underlying pathophysiology of DSD and the strengths and weaknesses of the tests that can be performed should be discussed with the parents and affected young person and tests undertaken in a timely fashion. This clinician should be part of a multidisciplinary team experienced in management of DSD and should ensure that the affected person and parents are as fully informed as possible and have access to specialist psychological support. Finally, in the field of rare conditions, it is imperative that the clinician shares the experience with others through national and international clinical and research collaboration.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.