ArticleMicrobial ecology2011
Phylogenetically diverse cultivable fungal community and polyketide synthase (PKS), non-ribosomal peptide synthase (NRPS) genes associated with the South China Sea sponges.
Article in Microbial ecology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 67 citations in OpenAlex.
- Endophytic Fungi Associated with Seaweeds as Potential Producers of Antimicrobial Compounds.Marine biotechnology (New York, N.Y.) · 2026Article
- Exploration of inactive metabolic pathways in AntarcticIMA fungus · 2026Article
- Marine Mycobiomes Colonize Mediterranean Sponge Hosts in a Random Fashion.Microbial ecology · 2025Article
- From marine neglected substrata new fungal taxa of potential biotechnological interest: the case ofFrontiers in microbiology · 2024Article
- Effects of Epigenetic Modification and High Hydrostatic Pressure on Polyketide Synthase Genes and Secondary Metabolites ofMarine drugs · 2023Article
- Diversity and Biosynthetic Potential of Fungi Isolated from St. John's Island, Singapore.International journal of molecular sciences · 2023Article
- Antitumor Potential of Seaweed Derived-Endophytic Fungi.Antibiotics (Basel, Switzerland) · 2019Review
- Fungal diversity of mangrove-associated sponges from New Washington, Aklan, Philippines.Mycology · 2019Article
- Secondary metabolites (SMs) ofRSC advances · 2018Review
- Diversity and communities of culturable endophytic fungi from different tree peonies (geoherbs and non-geoherbs), and their biosynthetic potential analysis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2018Article
- Diversity, host-specificity and stability of sponge-associated fungal communities of co-occurring sponges.PeerJ · 2018Article
- Review
- Elucidating the Diversity of Aquatic Microdochium and Trichoderma Species and Their Activity against the Fish Pathogen Saprolegnia diclina.International journal of molecular sciences · 2016Article
- A High-Level Fungal Diversity in the Intertidal Sediment of Chinese Seas Presents the Spatial Variation of Community Composition.Frontiers in microbiology · 2016Article
- Comparisons of the fungal and protistan communities among different marine sponge holobionts by pyrosequencing.Microbial ecology · 2014Article
- Diversity of cultivable fungi associated with Antarctic marine sponges and screening for their antimicrobial, antitumoral and antioxidant potential.World journal of microbiology & biotechnology · 2014Article
- Article
- Diversity and antimicrobial activity of culturable fungi isolated from six species of the South China Sea gorgonians.Microbial ecology · 2012Article
- Culturable endophytes of medicinal plants and the genetic basis for their bioactivity.Microbial ecology · 2012Article
- Diversity of nonribosomal peptide synthetase genes in the microbial metagenomes of marine sponges.Marine drugs · 2012Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Compared with sponge-associated bacteria, the phylogenetic diversity of fungi in sponge and the association of sponge fungi remain largely unknown. Meanwhile, no detection of polyketide synthase (PKS) or non-ribosomal peptide synthase (NRPS) genes in sponge-associated fungi has been attempted. In this study, diverse and novel cultivable fungi including 10 genera (Aspergillus, Ascomycete, Fusarium, Isaria, Penicillium, Plectosphaerella, Pseudonectria, Simplicillium, Trichoderma, and Volutella) in four orders (Eurotiales, Hypocreales, Microascales, and Phyllachorales) of phylum Ascomycota were isolated from 10 species marine sponges in the South China Sea. Eurotiales and Hypocreales fungi were suggested as sponge generalists. The predominant isolates were Penicillium and Aspergillus in Eurotiales followed by Volutella in Hypocreales. Based on the conserved Beta-ketosynthase of PKS and A domain of NRPS, 15 polyketide synthases, and four non-ribosomal peptides synthesis genes, including non-reducing and reducing PKSs and hybrid PKS-NRPS, were detected in these fungal isolates. A lateral gene transfer event was indicated in the comparison between the phylogenetic diversity of 18S rRNA genes and β-ketoacyl synthase domain sequences. Some fungi, especially those with PKS or NRPS genes, showed antimicrobial activity against P. fluorescens, S. aureus and B. subtilis. It was the first time to investigate PKS and NRPS genes in sponge-associated fungi. Based on the detected antibiotics biosynthesis-related PKS and NRPS genes and antimicrobial activity, the potential ecological role of sponge-associated fungi in the chemical defense for sponge host was suggested. This study extended our knowledge of sponge-associated fungal phylogenetic diversity and their potential roles in the chemical defense.
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