Evidence map›Paper›PMID 21519873›Full record

ReviewHead and neck pathology2011

Pseudotumor of the tracheal-laryngeal junction with unusual morphologic features caused by Rhodococcus equi infection.

Shreeram Akilesh, Sara Cross, Katherine Kimmelshue, Nigar Kirmani, Louis P Dehner, Samir K El-Mofty

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in Head and neck pathology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Pleural empyema with endobronchial mass due toWorld journal of clinical cases · 2024
    Article
  3. Article
  4. Pulmonary Malakoplakia byCase reports in infectious diseases · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shreeram AkileshDepartment of Pathology and Immunology, Barnes-Jewish Hospital, St. Louis, MO 63110, USA. akilesh78@gmail.com
Sara Cross
Katherine Kimmelshue
Nigar Kirmani
Louis P Dehner
Samir K El-Mofty
Barnes-Jewish Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious pseudotumors are unusual proliferations of histiocytes in response to certain microbial organisms. Occasionally this process may involve large airways, producing a mass lesion that may cause respiratory obstruction. Infectious pseudotumors can be confused with malignancy in their radiologic appearance and clinical presentation. We present a case of an aggressive endotracheal pseudotumor associated with Rhodococcus equi infection in a patient with advanced HIV disease. Microscopically, the lesion was composed of sheets of epithelioid histiocytes with large, strongly eosinophilic intra-cytoplasmic granules and features of malakoplakia. In this report, we review the literature of these unusual lesions and compare them to cases of conventional malakoplakia involving the large airways. We also explore the pathogenetic mechanisms that may contribute to the distinctive histologic appearance of Rhodococcus-associated pseudotumors.

Indexed as

Actinomycetales InfectionsAIDS-Related Opportunistic InfectionsDiagnosis, DifferentialHistiocytesHIV InfectionsHumansLarynxMalacoplakiaMaleMiddle AgedRhodococcus equiTrachea

Identifiers

PMID21519873
PMCPMC3210230
OpenAlexW2168060624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.